All Studies

Antineoplastic Drug Synergy of Artesunate with Navitoclax in Models of High-Grade Serous Ovarian Cancer.

Researchers found artesunate, a drug for severe malaria, enhances cell death in ovarian cancer when combined with navitoclax. This combo shows promising antineoplastic effects in both cell and animal models, hinting at a potential new treatment option for ovarian cancer.

McCorkle JR et al (2024).
Cancers (Basel).
PubMed:
38610999

UHPLC-MS/MS analysis and protective effects on neurodegenerative diseases of phenolic compounds in different parts of Diospyros kaki L. cv. Mopan.

Scientists identified and quantified 75 phenolic compounds in persimmon, showing neuroprotective effects against oxidative stress and neuroinflammation. Fruit extract showed strongest activity, informing targeted selection and development of persimmon for potential health benefits.

Zhao J et al (2024).
Food Res Int.
PubMed:
38609229

Bruceantinol works as a CDK2/4/6 inhibitor to inhibit the growth of breast cancer cells.

BOL from Brucea javanica inhibits breast cancer cell growth by targeting CDK2/4/6 and activating ERK. Potential anti-breast cancer treatment option.

Sun L et al (2024).
Chem Biol Interact.
PubMed:
38608999

Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis.

Study on Exo and their impact on prostate cancer growth and spread. Understanding their role could lead to new treatments or prevention strategies for the disease.

Jin M et al (2024).
Int Immunopharmacol.
PubMed:
38608471