Multi-omics analysis reveals promiscuous O-glycosyltransferases involved in the diversity of flavonoid glycosides in Periploca forrestii (Apocynaceae).

Wang X et al (2024).

Comput Struct Biotechnol J.

DOI:

10.1016/j.csbj.2024.02.028

PubMed:

38495554

A Prospective, Multicenter, Open-label Study to Evaluate the Safety and Efficacy of a Cream Containing Xyloglucan, Pea Protein, and Opuntia ficus-indica Extract Versus Calcipotriol/Betamethasone in Adult Patients with Mild-to-moderate Psoriasis.

Veraldi S et al (2024).

J Clin Aesthet Dermatol.

PubMed:

38495550

CRISPR/Cas9 revolutionizes Macleaya cordata breeding: a leap in sanguinarine biosynthesis.

Sun M et al (2024).

Hortic Res.

DOI:

10.1093/hr/uhae024

PubMed:

38495029

Maslinic acid alleviates intervertebral disc degeneration by inhibiting the PI3K/AKT and NF-κB signaling pathways.

Que Y et al (2024).

Acta Biochim Biophys Sin (Shanghai).

DOI:

10.3724/abbs.2024027

PubMed:

38495003

Withanone as an Emerging Anticancer Agent and Understanding Its Molecular Mechanisms: Experimental and Computational Evidence.

Researchers explored Withanone, a compound in Withania somnifera, as a potential safe cancer treatment. In silico and in vitro studies suggest anticancer activities and selective killing of cancer cells. Further research is needed for in vivo experiments and toxicity evaluation.

Stephen A et al (2024).

Curr Cancer Drug Targets.

DOI:

10.2174/0115680096290673240223043650

PubMed:

38494932

Aesculus hippocastanum extract and the main bioactive constituent β-escin as antivirals agents against coronaviruses, including SARS-CoV-2.

Summary: β-escin from Aesculus hippocastanum has anti-inflammatory effects and affects NF-κB signaling. It shows promising broad-spectrum antiviral activity against coronaviruses including SARS-CoV-2, with potential as a therapeutic option for respiratory virus outbreaks.

Peñaranda Figueredo FA et al (2024).

Sci Rep.

DOI:

10.1038/s41598-024-56759-y

PubMed:

38494515

Determination of Physicochemical Characteristics, Phytochemical Profile and Antioxidant Activity of Various Clover Honeys.

Sultana S et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202301880

PubMed:

38494456

Characterization of phenylalanine ammonia lyase and revealing flavonoid biosynthesis in Gymnema sylvestre R. Br through transcriptomic approach.

Researchers identified genes involved in flavonoid biosynthesis in Gymnema sylvestre through RNA extraction, sequencing, and in silico protein modeling. This information can enhance understanding of medicinal properties and potential applications of this plant.

Kalariya KA, Mevada RR and Das M (2024).

J Genet Eng Biotechnol.

DOI:

10.1016/j.jgeb.2023.100344

PubMed:

38494263