All Studies

Multiomic study of the protective mechanism of Persicaria capitata (Buch.-Ham. ex D.Don) H.Gross against streptozotocin-induced diabetic nephropathy in Guizhou miniature pigs.

Researchers studied Persicaria capitata as a potential treatment for diabetic nephropathy, a kidney disease associated with diabetes. Important for potential new drug development.

Diabetes Persicaria capitata
Wu Y et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155499
PubMed:
38492367

Eucalyptus Oils Phytochemical Composition in Correlation with Their Newly Explored Anti-SARS-CoV-2 Potential: in Vitro and in Silico Approaches.

"Eucalyptus citriodora essential oil shows strong potential against SARS-CoV-2. Globulol is a key compound. In silico and in vitro studies support its effectiveness. Promising for future COVID-19 research."

COVID-19Phytochemistry Eucalyptus
El-Shiekh RA et al (2024).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-024-01159-w
PubMed:
38492174

Genomic insights into the origin and evolution of spelt (Triticum spelta L.) as a valuable gene pool for modern wheat breeding.

Researchers analyzed genetic data from 416 wheat accessions to trace the origins of spelt, a primitive wheat subspecies crucial for modern breeding. Understanding spelt's evolution and genetic contribution aids in developing improved wheat varieties.

Genetics Triticum spelta
Wang Y et al (2024).
Plant Commun.
DOI:
10.1016/j.xplc.2024.100883
PubMed:
38491771

Foliar phenols and flavonoids level in pteridophytes: an insight to culturable fungal endophyte colonisation.

Study examined relationship between fungal endophyte colonization and levels of phenols and flavonoids in pteridophytes. Found significant correlations and identified specific fungal species. Important for understanding plant defense mechanisms and potential bioactive compounds.

Phytochemistry Adiantum capillus-venerisPteris vittata
Singha R et al (2024).
Arch Microbiol.
DOI:
10.1007/s00203-024-03880-1
PubMed:
38491263

Plant-Produced Therapeutic Crizanlizumab Monoclonal Antibody Binds P-Selectin to Alleviate Vaso-occlusive Pain Crises in Sickle Cell Disease.

Scientists cloned and expressed anti-P-selectin antibody genes in tobacco plants, successfully producing biofunctional therapeutic monoclonal antibody Crimab for Sickle Cell Disease treatment. This method can offer a cost-effective and scalable production alternative for essential treatments.

Pain Nicotiana tabacum
Yang T et al (2024).
Mol Biotechnol.
DOI:
10.1007/s12033-024-01110-z
PubMed:
38491245

Phyto-fabricated ZnO nanoparticles for anticancer, photo-antimicrobial effect on carbapenem-resistant/sensitive Pseudomonas aeruginosa and removal of tetracycline.

AS-ZnO NPs synthesized from Alternanthera sessilis leaf extract showed improved antimicrobial activity against various bacteria under white light conditions, higher toxicity to breast cancer cells, and enhanced catalytic potential for degrading tetracycline hydrochloride in wastewater. Great for designing antimicrobial formulations and environmental catalysts.

AntimicrobialCancer Alternanthera sessilis
Venkatraman G et al (2024).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-024-02984-8
PubMed:
38491194

Notoginsenoside R1 promotes Lgr5(+) stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling.

NGR1 from Panax notoginseng repairs damaged intestinal barrier in colitis mice by promoting Lgr5 stem cells through Wnt signaling pathway, reducing inflammation and enhancing epithelial repair. Potential therapeutic for IBD.

Gastroenterology Panax notoginseng
Yu ZL et al (2024).
Acta Pharmacol Sin.
DOI:
10.1038/s41401-024-01250-7
PubMed:
38491161

Identification of Hedyotis diffusa Willd-specific mRNA-miRNA-lncRNA network in rheumatoid arthritis based on network pharmacology, bioinformatics analysis, and experimental verification.

Tossers studied potential benefits of Hedyotis diffusa Willd on rheumatoid arthritis using gene analysis and experimental verification to target MMP9, finding its regulatory impact on RA progression. Implications for future traditional Chinese medicine research on RA.

ArthritisGenetics Hedyotis diffusa
Jiang J et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-56880-y
PubMed:
38491124
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