All Studies

Asiaticasics A-O, structurally intriguing coumarins from Toddalia asiatica with potential inflammatory inhibitory activity.

T. asiatica yielded new prenylated coumarins (asiaticasics A-O), showing anti-inflammatory activity, particularly compound 12. Compound 12 may reduce pyroptosis by inhibiting NLRP3 inflammasome. Morphological observation supported bioactivity evaluation.

Song SC et al (2024).
Phytochemistry.
PubMed:
38417721

Knocking out NtSARD1a/1b/1c/1d by CRISPR/CAS9 technology reduces the biosynthesis of salicylic acid (SA) and compromises immunity in tetraploid Nicotiana tabacum.

CRISPR/CAS9 was used to knock out NtSARD1 genes in tobacco, reducing SA biosynthesis and immune response to Pst DC3000 infection. Results show NtSARD1's crucial role in plant immunity. The study also highlights the utility of CRISPR/CAS9 in studying gene functions in polyploid plants.

Dai XY et al (2024).
Plant Sci.
PubMed:
38417717

Cellular and molecular mechanisms of oroxylin A in cancer therapy: Recent advances.

Research shows Oroxylin A from traditional Chinese medicine has potent anti-tumor effects through various biological mechanisms. Its safety and effectiveness warrant further clinical trials for potential cancer treatment.

Wang PX et al (2024).
Eur J Pharmacol.
PubMed:
38417609

Effects of Tripleurospermum caucasicum, Salvia rosmarinus and Tanacetum fruticulosum essential oils on aflatoxin B(1) production and aflR gene expression in Aspergillus flavus.

T. caucasicum and S. rosmarinus essential oils inhibit A. flavus growth and AFB production by 20.61-89.16%. Down-regulate aflR gene. Potential for controlling fungal contamination in food crops.

Mozafari Z et al (2024).
Int J Food Microbiol.
PubMed:
38417281

Rubus Occidentalis and its bioactive compounds against cancer: From molecular mechanisms to translational advances.

Researchers studied the potential anticancer effects of black raspberry due to its high content of beneficial compounds. Results suggest it could be a valuable addition to cancer treatment options.

Wang G et al (2023).
Phytomedicine.
PubMed:
38417241

Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice.

Researchers studied a new treatment combining PF-127 and phillyrin to enhance wound healing by modulating macrophages. This has potential for treating traumatic skin injuries.

Huang C et al (2024).
Cytokine.
PubMed:
38417214