Modulation of cellular metabolism and alleviation of bacterial dysbiosis by Aconiti Lateralis Radix Praeparata in non-small cell lung cancer treatment.

Researchers studied the effects of Fuzi on NSCLC. Fuzi showed promise in inhibiting NSCLC cell growth and inducing apoptosis. Understanding its mechanism may lead to new treatments for this deadly cancer.

Zhang W et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155099

PubMed:

38412665

High-quality genome assembly enables prediction of allele-specific gene expression in hybrid poplar.

Scientists obtained complete haplotype-phased genome assemblies for the parents of a hybrid poplar. They analyzed gene expression patterns and developed machine-learning models to predict allele-specific expression. These tools can aid in functional studies and understanding genetic factors influencing gene expression in poplar hybrids.

Shi TL et al (2024).

Plant Physiol.

DOI:

10.1093/plphys/kiae078

PubMed:

38412470

Therapeutic Polymer-Based Cannabidiol Formulation: Tackling Neuroinflammation Associated with Ischemic Events in the Brain.

Researchers developed a synthetic polymer nano-system for delivering CBD to improve its effectiveness in treating neuroinflammation. This system shows promising results in restoring mitochondrial function in cells after ischemic events. Worth considering for preclinical studies.

Chevalier MT et al (2024).

Mol Pharm.

DOI:

10.1021/acs.molpharmaceut.3c00244

PubMed:

38412451

Chemical Profiling and Enzyme Inhibitory Activities of Essential Oil Isolated from Pistacia Khinjuk Leaves: Insights On GC-MS Analysis and Skin Aging-Relevant Enzymes.

Pistacia khinjuk leaf oil contains compounds that inhibit collagenase and elastase enzymes, potentially reducing skin aging. Further research on bioavailability and toxicity is needed for cosmetic use.

Kamli H et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202302096

PubMed:

38412297

Anti-inflammatory Polyketides from an Endophytic Fungus Chaetomium sp. UJN-EF006 of Vaccinium bracteatum.

Wang YY et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202400002

PubMed:

38411310

Characterization of the complete chloroplast genome of 'Quanhong poplar' (Populus deltoides W. Bartram ex Humphry Marshall, 2011).

Scientists sequenced the chloroplast genome of 'Quanhong poplar', a rare reddish-purple cultivar, with 130 predicted genes. This data can aid breeders in developing plants with desired leaf colors.

Zhuang W et al (2024).

Mitochondrial DNA B Resour.

DOI:

10.1080/23802359.2024.2318391

PubMed:

38410200

Effectiveness of Novel Drug Delivery System using Curcumin in Alzheimer's Disease.

Study investigated natural product curcumin's effectiveness in treating Alzheimer's disease. Curcumin has anti-amyloid & anti-inflammatory properties, but poor bioavailability. Novel formulations improve bioavailability, potential treatment option for AD.

Urmila A, Kundlik R and Mathure D (2024).

Cent Nerv Syst Agents Med Chem.

DOI:

10.2174/0118715249279534240214111155

PubMed:

38409724

The Emergence of N. sativa L. as a Green Antifungal Agent.

Nigella sativa L. plant has potent therapeutic properties, with seed oil and thymoquinone inhibiting various fungi in studies. Valuable for potential medical applications in treating fungal infections.

Pandey R, Pandey B and Bhargava A (2024).

Mini Rev Med Chem.

DOI:

10.2174/0113895575282914240217060251

PubMed:

38409693