Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation.

HF, derived from Chinese herb, shows promise in treating RA with anti-inflammatory effects. Further research needed to understand how HF works to benefit RA patients.

Zhu J et al (2024).

BMC Complement Med Ther.

DOI:

10.1186/s12906-024-04397-2

PubMed:

38413973

Combined analysis of mRNA and miRNA transcriptomes reveals the regulatory mechanism of Xanthomonas arboricola pv pruni resistance in Prunus persica.

Researchers studied the impact of Xap on peach trees, finding it threatens yield and quality globally. Understanding this disease is crucial for effective management in peach cultivation.

Zhu P et al (2024).

BMC Genomics.

DOI:

10.1186/s12864-024-10113-8

PubMed:

38413907

Correction: Genome-wide identification, structural characterization and gene expression analysis of the WRKY transcription factor family in pea (Pisum sativum L.).

Xiong R et al (2024).

BMC Plant Biol.

DOI:

10.1186/s12870-024-04850-x

PubMed:

38413904

Publisher Correction: The complete plastome sequences of invasive weed Parthenium hysterophorus: genome organization, evolutionary significance, structural features, and comparative analysis.

Lubna et al (2024).

Sci Rep.

DOI:

10.1038/s41598-024-55391-0

PubMed:

38413785

Phytochemical variations antioxidant, and antibacterial activities among zebaria sumac (Rhus coriaria var. zebaria) populations in Iraq.

Scientists evaluated 50 accessions of Rhus coriaria var. zebaria in Iraq for phytochemical variations and antimicrobial activity. The plant is a rich source of essential oil compounds and minerals, with potential for cultivation and medicinal use.

Shahrivari S et al (2024).

Sci Rep.

DOI:

10.1038/s41598-024-53635-7

PubMed:

38413642

Olive oil nanoemulsion containing curcumin: antimicrobial agent against multidrug-resistant bacteria.

Nanoemulsions containing curcumin showed stable characteristics and antibacterial effects against resistant bacteria, enhancing ceftazidime activity and inhibiting biofilm formation. Promising for future clinical trials against multidrug-resistant Klebsiella pneumoniae infections.

Confessor MVA et al (2024).

Appl Microbiol Biotechnol.

DOI:

10.1007/s00253-024-13057-x

PubMed:

38413482

Koumine inhibits IL-1β-induced chondrocyte inflammation and ameliorates extracellular matrix degradation in osteoarthritic cartilage through activation of PINK1/Parkin-mediated mitochondrial autophagy.

Koumine, an alkaloid found in Gelsemium elegans, alleviates osteoarthritis in rats by increasing mitochondrial autophagy and reducing inflammation and cartilage erosion. This suggests potential for treating OA in humans.

Kong X et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116273

PubMed:

38412715

Notoginsenoside Fc, a novel renoprotective agent, ameliorates glomerular endothelial cells pyroptosis and mitochondrial dysfunction in diabetic nephropathy through regulating HMGCS2 pathway.

Notoginsenoside Fc (Fc) from Panax Notoginseng may protect against diabetic nephropathy, offering potential therapy for end-stage renal disease in diabetes.

Shen Y et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155445

PubMed:

38412666