RN0D, a galactoglucan from Panax notoginseng flower induces cancer cell death via PINK1/Parkin mitophagy.
RN0D from Panax notoginseng induces mitochondrial dysfunction in cancer cells, leading to cell death through ATP deprivation and mitophagy. Targets Galectin-3 and activates PINK1/Parkin pathway, showing promise as an anticancer therapeutic.
- Ji M et al (2024).
- Carbohydr Polym.
- PubMed:
- 38431406