Exosomes derived from Baicalin-pretreated bone mesenchymal stem cells improve Th17/Treg imbalance after hepatic ischemia-reperfusion via FGF21 and the JAK2/STAT3 pathway.

Baicalin-preteated BMSC-derived exosomes reduce hepatic I/R injury by suppressing inflammation, improving cell balance, and inducing FGF21 expression. Baicalin enhances therapeutic potential of exosomes for liver damage.

Zhang B et al (2024).

IUBMB Life.

DOI:

10.1002/iub.2810

PubMed:

38380586

The water-soluble subfraction from Artemisia argyi alleviates LPS-induced inflammatory responses via multiple pathways and targets in vitro and in vivo.

Chen L et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117364

PubMed:

38380576

Integrating serum pharmacochemistry and network pharmacology to explore the molecular mechanisms of Acanthopanax senticosus (Rupr. & Maxim.) Harms on attenuating doxorubicin-induced myocardial injury.

Acanthopanax, or Siberian ginseng, may help reduce the cardiotoxicity of chemotherapeutic drug doxorubicin, potentially enhancing its anticancer effects. This could lead to safer and more effective cancer treatments.

Zhang X et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117349

PubMed:

38380572

E. globulus leaf EO exhibits anti-inflammatory effects by regulating GSDMD-mediated pyroptosis, thereby alleviating neurological impairment and neuroinflammation in experimental stroke mice.

Researchers studied the chemical composition and anti-inflammatory properties of Eucalyptus globulus leaf essential oil from China. This plant is widely used in alternative medicine in developing countries.

Wang D et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117367

PubMed:

38380569

Histological, chemical and gene expression differences between western redcedar seedlings resistant and susceptible to cedar leaf blight.

Aldana JA et al (2024).

Front Plant Sci.

DOI:

10.3389/fpls.2024.1309762

PubMed:

38379949

Black seed oil reverses chronic antibiotic-mediated depression and social behaviour deficits via modulation of hypothalamic mitochondrial-dependent markers and insulin expression.

Chronic antibiotics can harm mitochondria, metabolism, and mood. Black seed oil improves depression, sociability, and metabolism in mice exposed to ampicillin. NSO could be a helpful treatment for antibiotic-induced impairments.

Adedokun MA et al (2024).

IBRO Neurosci Rep.

DOI:

10.1016/j.ibneur.2024.01.008

PubMed:

38379607

Colon targeting in rats, dogs and IBD patients with species-independent film coatings.

Ferraro F et al (2024).

Int J Pharm X.

DOI:

10.1016/j.ijpx.2024.100233

PubMed:

38379554

Characterization, antioxidant and antitumor activities of phenolic compounds from Amomum villosum Lour.

Researchers optimized ethanol extraction process of Lour/Sharen, identifying 35 bioactive compounds with antioxidant and antitumor properties. Ethyl acetate fraction showed highest content and activity, suggesting potential industrial applications.

Zhang M et al (2024).

Front Nutr.

DOI:

10.3389/fnut.2024.1327164

PubMed:

38379541