All Studies

Genome-wide analysis and expression pattern of the ZoPP2C gene family in Zingiber officinale Roscoe.

Researchers identified and studied the genome-scale of the PP2C gene family in ginger. Understanding these genes can provide insight into plant growth, development, signaling pathways, and responses to stresses.

Zhang P et al (2024).
BMC Genomics.
PubMed:
38245685

Hemerocallis citrina Baroni ameliorates chronic sleep deprivation-induced cognitive deficits and depressive-like behaviours in mice.

Hemerocallis citrina extract (HCE) was given to sleep-deprived mice. HCE improved cognitive function, reduced depression-like behaviors, and decreased inflammation in the hippocampus. HCE may be useful in preventing and treating cognitive decline and depression caused by sleep deprivation.

Jiang N et al (2024).
Life Sci Space Res (Amst).
PubMed:
38245346

Steroidal saponins from rhizome of Paris polyphylla var. chinensis and their anti-inflammatory, cytotoxic effects.

Scientists discovered five new compounds, parispolyosides A, E, and B-D, from the rhizome of Paris polyphylla var. chinensis. These compounds showed potential inhibitory effects on NO production and HepG2 cells. Molecular docking analysis suggested their mechanism of action on iNOS protein.

Guan L et al (2024).
Phytochemistry.
PubMed:
38244959

Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.

Hinokitiol from Chamaecyparis obtusa and Thuja plicata protects against ethanol-induced gastric injury by reducing hemorrhagic lesions and inflammation. It does this by regulating cellular iron levels, suggesting it could be used to prevent or improve gastric injury.

Zhao M et al (2024).
Eur J Pharmacol.
PubMed:
38244759

α-Hederin promotes ferroptosis and reverses cisplatin chemoresistance in non-small cell lung cancer.

Researchers investigated the effects of α-Hederin, a natural compound, on cisplatin resistance in non-small cell lung cancer (NSCLC). Understanding this interaction is crucial for improving chemotherapy outcomes in NSCLC patients.

Han S et al (2024).
Aging (Albany NY).
PubMed:
38244586

Network Pharmacology Analysis and In Vitro Validation of the Active Ingredients and Potential Mechanisms of Gynostemma Pentaphyllum Against Esophageal Cancer.

Researchers investigated the potential anti-esophageal cancer effects of Gynostemma pentaphyllum Thunb. Makino. Understanding its active components and mechanisms can lead to improved treatment options for esophageal cancer.

Guo J et al (2024).
Comb Chem High Throughput Screen.
PubMed:
38243957

Phloretin: a comprehensive review of its potential against diabetes and associated complications.

Phloretin, found in apples, has possible antidiabetic properties. This review explores its physical properties, pharmacokinetics, and pharmacodynamics, highlighting the need for more research on its therapeutic potential for diabetes.

Shelke V et al (2024).
J Pharm Pharmacol.
PubMed:
38243397