Integrated metabolome and transcriptome analysis reveals the regulatory mechanism of low nitrogen-driven biosynthesis of saponins and flavonoids in Panax notoginseng.

Cun Z et al (2024).

Gene.

DOI:

10.1016/j.gene.2024.148163

PubMed:

38224922

Hedscandines A-C, three undescribed indole alkaloids from Hedyotis scandens with their anti-MRSA activity.

Wang YJ et al (2024).

Phytochemistry.

DOI:

10.1016/j.phytochem.2024.113988

PubMed:

38224846

Intranasal administration of the essential oil from Perillae Folium ameliorates social defeat stress-induced behavioral impairments in mice.

Researchers investigated the antidepressant mechanism of essential oil from Perillae Folium (PFEO). PFEO is commonly used in traditional Chinese medicine to treat depression. The study aims to uncover the specific mechanism behind its antidepressant effects.

Nguyen LTH et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117775

PubMed:

38224793

Comparative analysis of antioxidant and fatty acid composition in avocado (Persea americana Mill.) fruits: Exploring regional and commercial varieties.

Purple-skinned avocado varieties from Madeira Island, Portugal have high antioxidant qualities and lipid content, including uncommon arachidonic acid. Harvest timing influences fatty acid content, making them promising for future use.

Gonçalves D et al (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2024.138403

PubMed:

38224668

Phytochemical Analysis, acetylcholinesterase inhibition, antidiabetic and antioxidant activity of Atriplex halimus L. (Amaranthaceae Juss.).

Mediterranean saltbush contains beneficial compounds like phenols and flavonoids, which have antioxidant properties. These compounds also have potential health benefits against diabetes and acetylcholinesterase-related conditions. Enzyme activities are linked to the presence of terpenes, sterols, saponins, coumarins, and carotenoids.

Mkaddem Guedri M et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202301941

PubMed:

38224199

Response surface methodology based development of an optimized polyherbal formulation and evaluation of its anti-diabetic and anti-obesity potential in high-fat diet-induced obese mice.

Researchers created a mix of edible seeds to test its effect on diabetes and obesity in mice. The results could potentially help develop a new treatment for these conditions.

Tanisha, Venkategowda S and Majumdar M (2023).

J Tradit Complement Med.

DOI:

10.1016/j.jtcme.2023.07.002

PubMed:

38223811

Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials.

This study reviewed clinical evidence on using herbal medicine to manage osteoporosis, which is a chronic skeletal disease causing low bone density and increased fracture risk.

Karimi SM, Bayat M and Rahimi R (2023).

J Tradit Complement Med.

DOI:

10.1016/j.jtcme.2023.08.001

PubMed:

38223808

Triptolide alleviates the development of inflammation in ankylosing spondylitis via the NONHSAT227927.1/JAK2/STAT3 pathway.

Triptolide, an ingredient in traditional Chinese medicine, shows promise in treating ankylosing spondylitis (AS) by regulating the long non-coding RNA NONHSAT227927.1. This study demonstrates that Triptolide reduces inflammation in AS-fibroblast-like synoviocytes (FLSs) and inhibits the JAK2/STAT3 pathway via NONHSAT227927.1.

Ding X et al (2023).

Exp Ther Med.

DOI:

10.3892/etm.2023.12305

PubMed:

38223328