All Studies

A rapid localization and analysis method for isoquinoline alkaloids with fluorescence in Coptis chinensis Franch. By fabricating the nano-silver sol as a substrate for surface-enhanced Raman spectroscopy.

Scientists developed a fast and sensitive method using surface-enhanced Raman spectroscopy to analyze traditional Chinese medicines (TCMs). This method overcomes limitations of traditional detection methods and helps ensure the quality and safety of TCMs.

Phytochemistry Coptis chinensis
Xie M et al (2024).
Anal Chim Acta.
DOI:
10.1016/j.aca.2023.342067
PubMed:
38182374

Production of functional recombinant roseltide rT1 antimicrobial peptide in tobacco plants.

Scientists successfully produced functional recombinant roseltide rT1 peptide in tobacco plants, which has antimicrobial properties and therapeutic applications for inflammatory lung diseases. This provides a rapid and cost-effective method for producing this important antimicrobial peptide for use in the food and therapeutic industries.

Antimicrobial Hibiscus sabdariffaNicotiana tabacum
Khalifeh-Kandy AS, Nayeri FD and Ahmadabadi M (2024).
J Biotechnol.
DOI:
10.1016/j.jbiotec.2023.12.018
PubMed:
38181983

Protective role of madecassoside from Centella asiatica against protein L-isoaspartyl methyltransferase deficiency-induced neurodegeneration.

PIMT protein repairs brain protein damage linked to aging. Mice without PIMT showed anxiety and cognitive issues, but treatment with MA reversed symptoms. MA could help treat anxiety and cognitive impairments in neurodegenerative diseases.

Neuroscience Centella asiatica
Ling Z et al (2024).
Neuropharmacology.
DOI:
10.1016/j.neuropharm.2023.109834
PubMed:
38181970

Oleander attenuates hepatic inflammation in a TLR4-independent manner and by favorable modulation of hepatocellular global metabolome that supports cytoprotection.

Nerium oleander, a plant used in traditional medicine, has hepatoprotective effects according to Indian and Chinese literature. Relevant for potential treatments of liver-related metabolic diseases.

Immunology Nerium oleander
Dey P et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117717
PubMed:
38181937

Protective effect of a hydromethanolic extract from Fraxinus excelsior L. bark against a rat model of aluminum chloride-induced Alzheimer's disease: Relevance to its anti-inflammatory and antioxidant effects.

Fraxinus excelsior (ash) has various beneficial properties including antioxidant and anti-inflammatory effects. It has been traditionally used to treat neurological disorders. This study investigates its potential effectiveness in Alzheimer's disease, which involves amyloid-beta, oxidative stress, and neuroinflammation.

ImmunologyNeuroscience Fraxinus excelsior
Iranpanah A et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117708
PubMed:
38181932

Codonopsis lanceolata polysaccharide ameliorates high-fat diet induced-postpartum hypogalactia via stimulating prolactin receptor-mediated Jak2/Stat5 signaling.

Researchers found that Codonopsis lanceolata polysaccharide improved weight gain, liver health, metabolic abnormalities, mammary gland development, and lactation performance in mice with hypogalactia induced by a high-fat diet. This suggests a potential use of traditional Chinese medicine for treating hypogalactia.

Immunology Codonopsis lanceolata
Chen S et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.129114
PubMed:
38181915

Coptisine inhibits aggressive and proliferative actions of fibroblast like synoviocytes and exerts a therapeutic potential for rheumatoid arthritis.

Coptisine, a compound from Chinese herb, has anti-tumor effect but its impact on rheumatoid arthritis (RA) is unclear. This study investigates coptisine's ability to control synovial proliferation in RA and its mechanism(s).

ArthritisCancer Coptis chinensis
Xu F et al (2024).
Int Immunopharmacol.
DOI:
10.1016/j.intimp.2023.111433
PubMed:
38181676
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