All Studies

Ethnobotanical study of traditional medicinal plants used by the local people in Habru District, North Wollo Zone, Ethiopia.

This study explores the use of medicinal plants in the Habru District of Ethiopia. The objective is to gather information on the plant species and traditional practices used by the local community to treat human ailments.

Ethnobotany Allium sativumCapsicum annuumMyrtus communisOcimum lamiifoliumOlea europaeaRuta chalepensisVerbascum sinaiticum
Alemu M et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00644-x
PubMed:
38178202

Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke.

Study investigated the effects of Atractylenolide I, Atractylenolide III, and Paeoniflorin on promoting angiogenesis after stroke. Findings could contribute to potential therapies for improving outcomes in stroke patients.

CardiologyNeuroscience Atractylodes macrocephala
Li H et al (2024).
Chin Med.
DOI:
10.1186/s13020-023-00872-z
PubMed:
38178130

A crossover randomized controlled trial examining the effects of black seed (Nigella sativa) supplementation on IL-1β, IL-6 and leptin, and insulin parameters in overweight and obese women.

This study examined the impact of Nigella sativa oil supplementation on overweight/obese women. The results suggest that NS oil may help manage inflammation and obesity by affecting blood mRNA expressions and levels of certain proteins.

ImmunologyObesity Nigella sativa
Razmpoosh E et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04226-y
PubMed:
38178093

Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in C2C12 myotubes and HepG2 hepatocytes.

Sugarcane top extract activates mitochondrial energy metabolism and increases PGC-1α levels in muscle and liver cells. This may have positive effects on tissue health and could have nutraceutical applications.

Genetics Saccharum officinarum
Iwata K et al (2024).
Nat Prod Bioprospect.
DOI:
10.1007/s13659-023-00423-x
PubMed:
38177614

A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.

Researchers created a dihydromyricetin-loaded hydrogel called PCD, which has antioxidant and anti-inflammatory properties. PCD promotes wound healing, showing potential to treat diabetic wounds.

Diabetes Phellinus igniarius
Yang J et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.129124
PubMed:
38176509

Preparation of polypeptide-metal complexes-coated Hosenkoside A and its inhibitory effect in cervical cancer.

Hosenkoside A from Impatiens balsamina seeds has anti-cervical cancer effects by inhibiting HDAC3, blocking STAT3 activation. Encapsulating it into PMC enhances targeted and sustained-release drug delivery, improving anti-tumor effects.

Cancer Impatiens balsamina
Wang Y et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.129177
PubMed:
38176488

Polysaccharide of Asparagus cochinchinensis (Lour.) Merr regulates macrophage immune response and epigenetic memory through TLR4-JNK/p38/ERK signaling pathway and histone modification.

The researchers investigated the relationship between the immune memory of macrophages and histone modifications. They found that the polysaccharide of Asparagus cochinchinensis enhances macrophages' immune function, but it is unclear if this is linked to immune memory and histone modification.

Immunology Asparagus cochinchinensis
Xie XD et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155294
PubMed:
38176271

In-silico evaluation of natural alkaloids against the main protease and spike glycoprotein as potential therapeutic agents for SARS-CoV-2.

Scientists studied 102 alkaloids and found six from the lotus plant that can potentially treat COVID-19 by targeting the spike protein and protease of SARS-CoV-2, aiding drug discovery with minimal side effects.

COVID-19Phytochemistry Nelumbo nucifera
Shah M et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0294769
PubMed:
38175855
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