GeoBotanical: All Studies

4569.

Isolation of plant-derived exosome-like nanoparticles (PDENs) from Solanum nigrum L. berries and Their Effect on interleukin-6 expression as a potential anti-inflammatory agent.

Researchers isolated and analyzed plant-derived exosome-like nanoparticles (PDENs) from black nightshade berries. PDENs showed anti-inflammatory properties by decreasing IL-6 expression in stimulated cells. PDENs are easier and cheaper to obtain than animal cell-derived exosomes, offering a potential alternative treatment for inflammation.

Immunology Solanum nigrum

Emmanuela N et al (2024).; PLoS One.
DOI:: 10.1371/journal.pone.0296259
PubMed:: 38175845

4570.

Akebia saponin D attenuates allergic airway inflammation through AMPK activation.

Akebia saponin D (ASD), extracted from Dipsacus asper Wall, inhibits inflammation in lung cells and mice through AMPK activation, suggesting ASD as a potential treatment for allergic airway inflammation.

Immunology Phytochemistry Dipsacus asper

Xuan L et al (2024).; J Nat Med.
DOI:: 10.1007/s11418-023-01762-2
PubMed:: 38175326

4571.

Hypericum perforatum: a comprehensive review on pharmacognosy, preclinical studies, putative molecular mechanism, and clinical studies in neurodegenerative diseases.

St. John's wort shows promise in treating neurodegenerative diseases due to its anti-inflammatory and antioxidant properties, as well as its ability to regulate neurotransmitter systems. Animal studies have shown improved cognitive performance and nerve cell survival. More research is needed for clinical applications.

Neuroscience Hypericum perforatum

Suryawanshi MV et al (2024).; Naunyn Schmiedebergs Arch Pharmacol.
DOI:: 10.1007/s00210-023-02915-6
PubMed:: 38175276

4572.

Triptolide promotes nerve repair after cerebral ischemia reperfusion injury by regulating the NogoA/NgR/ROCK pathway.

Triptolide, derived from traditional Chinese medicine, reduces nerve damage after brain injury by inhibiting the NogoA/NgR/ROCK pathway and enhancing synaptic function. Promising treatment option for cerebral ischemia-reperfusion injury.

Cardiology Tripterygium wilfordii

Zhang H et al (2024).; Folia Neuropathol.
DOI:: 10.5114/fn.2023.133065
PubMed:: 38174687

4573.

A comprehensive review on traditional applications, phytochemistry, pharmacology, and toxicology of Thymus serpyllum.

Thymus serpyllum, a traditional medicinal shrub from India, has potential for developing new drugs. Its essential oil has various pharmacological properties, but more studies are needed to validate its efficacy and explore its applications in medicine and food.

Phytochemistry Thymus serpyllum

Salaria D et al (2023).; Indian J Pharmacol.
DOI:: 10.4103/ijp.ijp_220_22
PubMed:: 38174535

4574.

Transcription of the antisense long non-coding RNA, SUPPRESSOR OF FEMINIZATION, represses expression of the female-promoting gene FEMALE GAMETOPHYTE MYB in the liverwort Marchantia polymorpha.

Researchers found that a specific RNA called SUF plays a key role in determining the sex of Marchantia polymorpha plants. They discovered that when SUF is present, the plant develops as male, but by inserting a sequence into SUF, the plant can develop as female. The study highlights the importance of SUF transcription in controlling sex differentiation in M. polymorpha.

Genetics Marchantia polymorpha

Kajiwara T et al (2024).; Plant Cell Physiol.
DOI:: 10.1093/pcp/pcad170
PubMed:: 38174428

4575.

Characteristics of the complete chloroplast genome of Saxifragaceae species Bergenia purpurascens (Hook. f. et Thoms.) Engl.

The researchers sequenced the complete chloroplast genome of a traditional Chinese medicinal plant. This data will help understand the plant's evolutionary patterns and aid further research in its systematics.

Genetics Bergenia purpurascens

Ao L et al (2023).; Mitochondrial DNA B Resour.
DOI:: 10.1080/23802359.2023.2294895
PubMed:: 38173921

4576.

Vitex Negundo-Fe(3)O(4)-CuO green nanocatalyst (VN-Fe(3)O(4)-CuO): synthesis of pyrazolo[3,4-c]pyrazole derivatives via the cyclization of isoniazid with pyrazole and their antimicrobial activity, cytotoxicity, and molecular docking studies.

Scientists developed a new compound with potential as a treatment for infectious diseases. It showed strong antibacterial and antifungal activity, better than standard drugs, along with low cytotoxicity. Molecular docking and dynamics simulations supported its efficacy. The compound was synthesized using a nanocatalyst.

Antimicrobial Vitex negundo

Akbar I et al (2024).; RSC Adv.
DOI:: 10.1039/d3ra06771h
PubMed:: 38173593