Mechanistic role of Syzygium cumini (L.) Skeels in glycation induced diabetic nephropathy via RAGE-NF-κB pathway and extracellular proteins modifications: A molecular approach.

Researchers investigated the molecular mechanism of Syzygium cumini's interaction with the AGEs-RAGE-NF-κB pathway. This ancient medicinal plant may be beneficial in treating diabetic nephropathy due to its anti-glycemic, anti-glycation, anti-inflammatory, and antioxidant properties.

Apte MM, Khattar E and Tupe RS (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117573

PubMed:

38110133

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids.

Peng B et al (2023).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.3c06785

PubMed:

38109879

A novel off-line multi-dimensional high-speed countercurrent chromatography strategy for preparative separation of bioactive neolignan isomers from Piper betle. L.

Xiao CY et al (2023).

J Chromatogr B Analyt Technol Biomed Life Sci.

DOI:

10.1016/j.jchromb.2023.123965

PubMed:

38109812

Ganoderma lucidum spore oil synergistically enhances the function of cyclophosphamide in the prevention of breast cancer metastasis.

Ganoderma lucidum is a Chinese herbal medicine with potential as additional cancer therapy, but its specific effects and mechanisms are still unknown.

Lian S et al (2023).

J Chin Med Assoc.

DOI:

10.1097/JCMA.0000000000001038

PubMed:

38109372

Use of Nile tilapia (Oreocromis niloticus) processing residues in the production of pâtés with the addition of oregano (Origanum vulgare) essential oil.

Matiucci MA et al (2023).

PLoS One.

DOI:

10.1371/journal.pone.0296106

PubMed:

38109370

Lead optimization of Allium sativum L. compounds for PTP1B inhibition in diabetes treatment: in silico molecular docking and dynamics simulation.

This study investigated how natural compounds bind to PTP1B, a drug target for diabetes. The optimized compounds had good binding scores and the kaempferol compounds showed stability. The study identified potential targets and pathways for anti-PTP1B effects, aiding diabetes medication development.

Ojo OA et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2294179

PubMed:

38109128

The Fertility tracks of Pollen Tube in the ovary of Solanum Nigrum by Three-Dimensional Reconstruction.

Scientists studied pollen tube growth in a plant species and found that successful seed germination depends on fertilization. Proximity between ovules and pollen tubes increases fertilization chances. Fertilized ovules show structural changes and impact seed germination rate. Unfertilized ovules have low germination success.

Ming X et al (2023).

J Microsc.

DOI:

10.1111/jmi.13257

PubMed:

38108660

Chemical Composition and Biological Activities of the Essential Oil from Citrus reticulata Blanco Peels Collected from Agrowastes.

Job JT et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202301223

PubMed:

38108562