Haplotype-resolved genome of heterozygous African cassava cultivar TMEB117 (Manihot esculenta).

Landi M et al (2023).

Sci Data.

DOI:

10.1038/s41597-023-02800-0

PubMed:

38071206

Antimicrobial and biocompatibility nature of methanol extract of Lannea coromandelica bark and edible coating film preparation for fruit preservation.

Researchers studied the antimicrobial activity of Lannea coromandelica bark extract against fungi and bacteria, and found it to be effective. They also determined its biocompatibility and its potential for preserving fruit by creating an edible coating with chitosan. Coated fruit had improved quality compared to uncoated fruit.

Chau TP et al (2023).

Environ Res.

DOI:

10.1016/j.envres.2023.117861

PubMed:

38070851

Hypoglycemic activity of immature persimmon (Diospyros kaki Thunb.) extracts and its inhibition mechanism for α-amylase and α-glucosidase.

Immature persimmons contain Hederagenin, Ursolic acid, and Quercetin dehydrate, which inhibit α-amylase and α-glucosidase enzymes, reducing hyperglycemia. They have potential for treating diabetes mellitus.

Han Z et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.128616

PubMed:

38070815

Danshensu inhibits SARS-CoV-2 by targeting its main protease as a specific covalent inhibitor and discovery of bifunctional compounds eliciting antiviral and anti-inflammatory activity.

Salvia miltiorrhiza and its active ingredient Danshensu have shown to inhibit SARS-CoV-2 and possess anti-inflammatory properties. Danshensu is a covalent inhibitor of the 3CL protease of SARS-CoV-2, making it a potential candidate for targeted drug development against COVID-19.

Wang R et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.128623

PubMed:

38070810

Genome-wide identification and expression profiling of the WRKY gene family reveals abiotic stress response mechanisms in Platycodon grandiflorus.

Yu H et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.128617

PubMed:

38070802

Acute and chronic toxicity in Sprague-Dawley rats of orally-administered total lignans from Arctii Fructus, a potential therapeutic drug for diabetes.

TLAF, a compound from Arctii Fructus, showed low toxicity in rats at 1,800 mg/kg for 26 weeks. It has potential for clinical treatment of diabetes.

Mei J et al (2024).

Regul Toxicol Pharmacol.

DOI:

10.1016/j.yrtph.2023.105542

PubMed:

38070762

Antifungal effects of carvacrol, the main volatile compound in Origanum vulgare L. essential oil, against Aspergillus flavus in postharvest wheat.

Carvacrol, found in essential oils from Origanum vulgare L., can completely inhibit the growth of Aspergillus flavus in wheat grains, making it a potential biofumigant for preventing postharvest grain contamination. Carvacrol induces oxidative stress and damages the plasma membrane and DNA of A. flavus.

Duan WY et al (2023).

Int J Food Microbiol.

DOI:

10.1016/j.ijfoodmicro.2023.110514

PubMed:

38070224

Investigating the multitargeted anti-diabetic potential of cucurbitane-type triterpenoid from Momordica charantia: an LC-MS, docking-based MM\GBSA and MD simulation study.

A cucurbitane-type triterpene exhibited anti-diabetic properties, showing favorable binding energy, stability, pharmacokinetic, and toxicity properties. It has potential as an anti-diabetic drug candidate, but further research is needed.

Famuyiwa SO et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2291174

PubMed:

38069604