All Studies

The Protective Effect of Marsdenia tenacissima against Cisplatin-Induced Nephrotoxicity Mediated by Inhibiting Oxidative Stress, Inflammation, and Apoptosis.

This study shows that the traditional Chinese medicine (TCM) MT can enhance the anti-tumor effect of cisplatin (Cis) while reducing its toxic side effects, specifically nephrotoxicity. MT improves renal function, decreases inflammation, and regulates apoptosis through the Nrf2 and NF-κB pathways. Use MT as an adjuvant to mitigate Cis-induced nephrotoxicity.

Immunology Marsdenia tenacissima
Zhang Z et al (2023).
Molecules.
DOI:
10.3390/molecules28227582
PubMed:
38005304

In Vitro Anti-Tumor and Hypoglycemic Effects of Total Flavonoids from Willow Buds.

Willow bud flavonoids showed anti-tumor effects on cervical, colon, and breast cancer cells and displayed hypoglycemic properties, indicating potential applications in food and pharmaceutical industries.

CancerDiabetesPhytochemistry Salix babylonica
Zhang P et al (2023).
Molecules.
DOI:
10.3390/molecules28227557
PubMed:
38005279

Ultrasonic-Assisted Extraction of Antioxidants from Perilla frutescens Leaves Based on Tailor-Made Deep Eutectic Solvents: Optimization and Antioxidant Activity.

Researchers found that extracting antioxidants from Perilla leaves using choline chloride-based deep eutectic solvents (DESs) had high antioxidant activity. This eco-friendly method could have various applications, but its cytotoxicity and biodegradability need further investigation.

Immunology Perilla frutescens
Jiao P et al (2023).
Molecules.
DOI:
10.3390/molecules28227554
PubMed:
38005276

Green Synthesis of Copper Oxide Nanoparticles from the Leaves of Aegle marmelos and Their Antimicrobial Activity and Photocatalytic Activities.

Copper oxide nanoparticles were synthesized from Aegle marmelos plant leaves and characterized. They exhibited antimicrobial activity and photodegraded organic dyes under sunlight. They can potentially be used in various applications, including medicine and environmental remediation.

Antimicrobial Aegle marmelos
Ali SG et al (2023).
Molecules.
DOI:
10.3390/molecules28227499
PubMed:
38005229

Zaluzanin C Alleviates Inflammation and Lipid Accumulation in Kupffer Cells and Hepatocytes by Regulating Mitochondrial ROS.

Zaluzanin C (ZC), a compound found in plants, has anti-inflammatory and antioxidant effects. It protects liver cells by reducing inflammation, improving mitochondrial function, and enhancing lipid metabolism. ZC could be an effective treatment for liver protection.

Immunology Laurus nobilis
Jung JW et al (2023).
Molecules.
DOI:
10.3390/molecules28227484
PubMed:
38005205

Effect of E. cava and C. indicum Complex Extract on Phorbol 12-Myristate 13-Acetate (PMA)-Stimulated Inflammatory Response in Human Pulmonary Epithelial Cells and Particulate Matter (PM)(2.5)-Induced Pulmonary Inflammation in Mice.

The study found that the natural composite ED could reduce lung inflammation caused by fine particulate matter. It inhibited gene expression and reduced cellular accumulation and mucus secretion, indicating its potential as a therapeutic agent for respiratory diseases.

Immunology Chrysanthemum indicum
Lee SG, Park CH and Kang H (2023).
Pharmaceutics.
DOI:
10.3390/pharmaceutics15112621
PubMed:
38004599

Carob Extract (Ceratonia siliqua L.): Effects on Dyslipidemia and Obesity in a High-Fat Diet-Fed Rat Model.

Researchers investigated the effects of carob extract and simvastatin on rats fed a high-cholesterol diet. They found that the combination reduced weight gain, lowered cholesterol levels, increased adiponectin, decreased leptin, and improved liver health. Carob may have potential in treating dyslipidemia and obesity.

Obesity Ceratonia siliqua
Rašković A et al (2023).
Pharmaceutics.
DOI:
10.3390/pharmaceutics15112611
PubMed:
38004588

Rubia cordifolia L. Attenuates Diabetic Neuropathy by Inhibiting Apoptosis and Oxidative Stress in Rats.

The study investigated the impact of L. (L.) roots in diabetic neuropathy using a rat model. It examined potential neuroprotective, antidiabetic, and analgesic mechanisms. This research is relevant for understanding diabetic neuropathy treatment options.

DiabetesImmunology Rubia cordifolia
Bana S et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16111586
PubMed:
38004451
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