All Studies

Cytotoxic and anti-metastatic effects of Hypericum perforatum olive oil extract in colorectal cancer cells and human bone marrow derived stem cells.

This study investigated the effects of olive oil extract on colorectal cancer cells and bone marrow-derived stem cells. Results showed reduced cell migration and colony formation, suggesting potential therapeutic benefits against colorectal cancer.

Yildirim H and Daşkan BE (2023).
Nat Prod Res.
PubMed:
37950737

Extraction of phenolic compounds from walnut green husk (Juglans regia L.) by Salting-Out extraction method.

This study found the best conditions for extracting phenolic compounds from walnut green husks using a method called salting-out extraction. The optimal conditions resulted in higher phenolic content and antioxidant activity compared to conventional methods. This research is important for extraction techniques and utilizing agricultural waste.

Barekat S et al (2023).
Prep Biochem Biotechnol.
PubMed:
37950423

Kaempferol-3-O-sophoroside contributes to modulation of depressive-like behavior in C57BL/6J mice by activating AMPK.

Researchers studied the main component in saffron, PCS-1, and its effect on a potential therapeutic target for depression called AMPK. They found that PCS-1 has antidepressive properties by activating AMPK. This suggests that targeting AMPK could be beneficial for treating depression.

Wang R et al (2023).
Br J Pharmacol.
PubMed:
37949672

Role of parthenolide in paclitaxel-induced oxidative stress injury and impaired reproductive function in rat testicular tissue.

Parthenolide, a plant extract, can alleviate testicular toxicity caused by paclitaxel, reducing oxidative stress and improving antioxidant levels and gene expression related to reproduction in rats, potentially offering a treatment for PTX-induced testicular damage.

Toraman E et al (2023).
Chem Biol Interact.
PubMed:
37949423

Wikstroemia indica (L.) C. A. Mey. Exerts analgesic activity by inhibiting NaV1.7 channel.

Researchers explored the pain-relieving effects of Wikstroemia indica, a medicinal plant with numerous benefits but no previous studies on analgesic properties. This finding holds significance for those seeking natural alternatives for pain relief.

Zhang K et al (2023).
J Ethnopharmacol.
PubMed:
37949328

Hepatotoxicity effects of Ageratina adenophora, as indicated by network toxicology combined with metabolomics and transcriptomics.

The study examined the toxic mechanisms of Ageratina adenophora (a invasive plant) using multiomics approach. The main toxic compounds were identified, and metabolites involved in amino acid and lipid metabolism were found. The plant induces liver inflammatory damage and affects nutrient metabolism and neuron conduction.

Huang R et al (2023).
Ecotoxicol Environ Saf.
PubMed:
37948940