(1)H NMR-based metabolomics study of the lipid profile of omega-3 fatty acid supplements and some vegetable oils.

Hasanpour M et al (2024).

J Pharm Biomed Anal.

DOI:

10.1016/j.jpba.2023.115848

PubMed:

37948777

Ternifoliasaponin, a new triterpenoid saponin from the roots of Gardenia ternifolia Schumach & Thonn (Rubiaceae).

A new compound, Ternifoliasaponin, along with four known compounds, were isolated from a plant. They were tested for antibacterial and antimicrobial activity, showing moderately sensitive effects against certain microorganisms.

Yaya H et al (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2023.2276388

PubMed:

37948554

Genome-wide association analysis of anthracnose resistance in the Yellow Bean Collection of Common Bean.

Researchers evaluated the Yellow Bean Collection (YBC) to understand anthracnose resistance in yellow beans. They identified genotypes with superior resistance and identified major-effect loci and candidate genes associated with resistance. This information can be used to develop strategies for disease control in common bean crops.

Kuwabo K et al (2023).

PLoS One.

DOI:

10.1371/journal.pone.0293291

PubMed:

37948396

HDAC inhibition by Nigella sativa L. sprouts extract in hepatocellular carcinoma: an approach to study anti-cancer potential.

Scientists studied the 5th day germinated sprouts of seeds for their potential as an anticancer therapy. The sprouts were found to inhibit HDAC activity and have antioxidant properties, making them a promising alternative for preventing liver diseases. Thymoquinone, a compound found in the sprouts, showed strong interaction with HDAC protein.

Algaissi A et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2279283

PubMed:

37948309

Virtual screening, pharmacokinetics & MD simulation study of active phytoconstituents of Ficus Carica Linn. against PPAR-γ in diabetes mellitus.

This study evaluated bioactive compounds from a small tree against PPAR-γ, a target for diabetes management. Quercetin-3-o-rutinoside and other compounds showed potential as anti-diabetic agents and may act as PPAR-γ agonists.

Deshpande N S, Dwivedi PSR and Revanasiddappa BC (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2279286

PubMed:

37948295

Analgesic effect of Centaurium erythraea and molecular docking investigation of the major component swertiamarin.

An Algerian traditional medicine extract was found to effectively reduce pain in rats, both peripherally and centrally. Molecular docking suggests the compound in the extract interacts well with pain-related proteins, validating its traditional use as an analgesic.

Chabane S et al (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2023.2278160

PubMed:

37948163

Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function.

Low molecular weight polysaccharide (GP) improves gut health and boosts immune system by increasing immune cells, cytokines, and beneficial gut bacteria while reducing harmful bacteria. GP could be a potential treatment for intestinal inflammatory diseases.

Song W et al (2023).

Gut Microbes.

DOI:

10.1080/19490976.2023.2276814

PubMed:

37948152

Supplementation with Manihot esculenta Crantz (Cassava) leaves' extract prevents recognition memory deficits and hippocampal antioxidant dysfunction induced by Amyloid-β.

Cassava leaves' extract (CAS) was tested on an Alzheimer's disease (AD)-like model induced by amyloid-beta (Aβ) 25-35 peptide. Results showed that CAS has neuroprotective effects on oxidative balance and memory deficits.

Carrazoni GS et al (2023).

Nutr Neurosci.

DOI:

10.1080/1028415X.2023.2280815

PubMed:

37948133