This study used network pharmacology, molecular docking, and in vivo experiments to investigate the potential of Artemisia annua in treating acute myocardial infarction. It identified key targets and pathways and demonstrated the extract's positive effects on ventricular function and reducing fibrosis.
Hypericum triquetrifolium Turra has been used in traditional medicine in the Mediterranean region. Despite extensive research on its essential oils, little is known about other potential health benefits.
Researchers found that extracts from Syzygium aromaticum and Alpinia purpurata can be used as alternative drugs to treat Candida krusei infections, which are highly lethal and resistant to fluconazole treatment. This offers potential new treatment options for combating this deadly fungal infection.
This study examined the chemical profiles of O. americanum and O. basilicum essential oils from their leaves and explored their antibacterial, antioxidant, and larvicidal properties. These plants are widely used in various industries, making the findings significant for food, cosmetic, and pharmaceutical applications.
Network pharmacology and experimental verification were used to study the effects of Semen Strychni on papillary carcinoma thyroid (PTC). Brucine was identified as a suitable marker and showed strong anti-PTC activity, indicating Semen Strychni's potential as a treatment for PTC.
Icariin, a natural compound from a Chinese herb, was found to negatively affect the development of zebrafish embryos. It disrupted thyroid development and hormone synthesis, indicating potential toxicity. Risk assessments should be done before using ICA in clinical practice.
Researchers developed a nanoformulation of costunolide (COST) to improve its anti-proliferative effects in colon cancer cells. The optimized formulation showed increased cytotoxicity, enhanced apoptosis, and altered gene expression compared to raw COST, making it more effective in killing cancer cells.
Scientists investigated the anticancer effects of rhein, a natural agent, in liver cancer. They identified its molecular targets and examined whether it can work with artemisinin derivatives to inhibit the disease. This research may lead to improved therapies for liver cancer.