All Studies

Inhibition of Acinetobacter baumannii Biofilm Formation by Terpenes from Oregano (Lippia graveolens) Essential Oil.

Oregano essential oil (OEO) and its compounds, carvacrol and thymol, effectively inhibit biofilms of the nosocomial pathogen . Carvacrol at 0.15 mg/mL achieved a 95% reduction, and sub-inhibitory concentrations reduced biofilm formation on surfaces. Terpenes show promise for preventing infections and overcoming antibiotic resistance.

Phytochemistry Lippia graveolens
Tapia-Rodriguez MR et al (2023).
Antibiotics (Basel).
DOI:
10.3390/antibiotics12101539
PubMed:
37887240

Purification and Characterization of Polyphenol Oxidase in the Fruits of Opuntia ficus-indica.

Researchers purified and characterized polyphenol oxidase (PPO) from fruits of [unknown]. PPO's optimal pH and temperature were determined for pyrogallol, catechol, and 4-methyl catechol. Pyrogallol was found to be the best substrate for PPO from [unknown].

Phytochemistry Opuntia ficus-indica
Demir D, Kabak S and Çağlayan K (2023).
Biology (Basel).
DOI:
10.3390/biology12101339
PubMed:
37887049

Inhibition of Phagocytosis by Silibinin in Mouse Macrophages.

Silibinin, derived from milk thistle, effectively inhibits macrophage activation by preventing morphological changes and reducing phagocytosis. It targets key inflammatory pathways, making it a potential anti-inflammatory agent with promising therapeutic properties.

Immunology Silybum marianum
Sun KH, Lee MY and Jeon YJ (2023).
Curr Issues Mol Biol.
DOI:
10.3390/cimb45100513
PubMed:
37886956

Chemical profiling of botanical extracts obtained in NADES systems using centrifugal partition chromatography combined with (13) C NMR dereplication-Hypericum perforatum as a case study.

Scientists have found that natural deep eutectic solvents (NADES) can effectively extract botanical ingredients. NADES are safe, eco-friendly, and versatile, but analyzing the extracted compounds is challenging due to their low concentration in the thick NADES solution.

Phytochemistry Hypericum perforatum
Kotland A, Thiery J and Hubert J (2023).
Phytochem Anal.
DOI:
10.1002/pca.3297
PubMed:
37886892

Preventive effects of inotodiol on polyinosinic-polycytidylic acid-induced inflammation in human dermal fibroblasts.

Inotodiol, a compound found in Chaga mushroom, has significant anti-inflammatory effects. It can suppress the inflammation induced by poly(I:C), which mimics double-strand RNA, in human dermal fibroblast cells. This suggests that inotodiol could be used as an effective anti-inflammatory agent in cosmetics.

Immunology Inonotus obliquus
Won GW et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e20556
PubMed:
37886743

Centella asiatica promotes antioxidant gene expression and mitochondrial oxidative respiration in experimental autoimmune encephalomyelitis.

Centella asiatica (Centella) does not improve cognitive function or reduce disease burden in multiple sclerosis (MS) in mice. However, it does increase antioxidant gene expression and mitochondrial respiratory activity, suggesting potential benefits in MS patients.

GeneticsImmunology Centella asiatica
Kundu P et al (2023).
Res Sq.
DOI:
10.21203/rs.3.rs-3393042/v1
PubMed:
37886497

Ethnobotanical Study of Medicinal Plants Used against Human Diseases in Zuway Dugda District, Ethiopia.

This study documented medicinal plants used in the Zuway Dugda district of Ethiopia. It involved interviews, market surveys, and observations from 100 informants. The collected data was analyzed using various methods. The findings can help expand the knowledge of traditional medicine and contribute to public health improvement.

Ethnobotany Asparagus africanusCordia africana
Megersa M, Nedi T and Belachew S (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/5545294
PubMed:
37886427

Developmental landscape of computational techniques to explore the potential phytochemicals from Punica granatum peels for their antioxidant activity in Alzheimer's disease.

Researchers prepared and studied a library of 1,000 compounds from peels to find antioxidants for Alzheimer's disease. Using computational calculations, they identified active compounds and performed molecular docking, optimization, and toxicity evaluation. Hesperidin showed promise as a potential drug for Alzheimer's treatment.

ImmunologyNeuroscience Punica granatum
Parveen S et al (2023).
Front Mol Biosci.
DOI:
10.3389/fmolb.2023.1252178
PubMed:
37886033
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