All Studies

In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer.

Researchers analyzed leaves for potential anti-cancer treatments, finding they targeted angiogenesis and neuropilins in breast cancer. In-silico analysis confirmed stability of Neuropilin complexes.

Zafar I et al (2023).
Front Chem.
PubMed:
37885828

RNA-sequencing analysis reveals novel genes involved in the different peel color formation in eggplant.

This study identified genes and a regulatory model related to color formation in eggplant. The findings enhance our understanding of the molecular mechanism behind different color variations in eggplant.

Li J et al (2023).
Hortic Res.
PubMed:
37885819

FlbZIP12 gene enhances drought tolerance via modulating flavonoid biosynthesis in Fagopyrum leptopodum.

Scientists studied a wild population of drought-tolerant buckwheat to enhance drought tolerance in cultivated buckwheat. Overexpressing a gene called FlbZIP12 in buckwheat increased drought tolerance and flavonoid contents. This research provides a basis for improving buckwheat's ability to withstand drought.

Wang A et al (2023).
Front Plant Sci.
PubMed:
37885669

Genetic diversity of Coffea arabica L. mitochondrial genomes caused by repeat- mediated recombination and RNA editing.

Scientists sequenced and characterized the mitochondrial genome of L., an important crop. This will enhance evolutionary studies, molecular breeding, and the development of molecular markers for improved agricultural practices.

Ni Y et al (2023).
Front Plant Sci.
PubMed:
37885664

Corylus avellana "Nocciola Piemonte": metabolomics focused on polar lipids and phenolic compounds in fresh and roasted hazelnuts.

This study analyzed the polar fraction of fresh and roasted hazelnut kernels and identified various phenolic compounds and polar lipids. The roasted kernels had three times higher lipid content and the most represented lipid classes were lyso-phospholipids and phospholipids. Certain compounds showed strong antioxidant activity and inhibited lipid peroxidation.

Cerulli A et al (2023).
Front Plant Sci.
PubMed:
37885660

"Cholinergic side Effect-Free anticancer drugs: paving the way for safer and more effective cancer treatment".

Study explores amla phytochemicals as potential inhibitors of Top1 protein in cancer. Aims to find alternative treatment without side effects from acetylcholinesterase inhibition. New medications could reduce irinotecan's side effects.

Ritu, Chandra P and Das A (2023).
J Biomol Struct Dyn.
PubMed:
37885319

Accessible gene borders establish a core structural unit for chromatin architecture in Arabidopsis.

Hi-C was used to study chromatin structure in Arabidopsis, tomato, maize, and Marchantia polymorpha genomes. Genes form folding domain units and neighboring genes form larger contact domains, with transcription factors binding to accessible regions contributing to gene domains and genome folding in plants.

Lee H and Seo PJ (2023).
Nucleic Acids Res.
PubMed:
37884483

Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome.

TCM can influence the gut microbiome to combat osteoporosis. This is because the gut microbiome affects inflammation, hormone levels, nutrient absorption, and bone mass. TCM herbs can regulate the gut microbiome and indirectly impact bone health. Puerarin specifically improves intestinal health and reduces inflammation caused by estrogen deficiency.

Li K et al (2023).
Am J Chin Med.
PubMed:
37884447