All Studies

Evaluation of berberine nanoparticles as a strategy to modulate acetylcholinesterase activity.

Berberine-loaded solid dispersions (SD) show potential as inhibitors of acetylcholinesterase enzyme (AChE) for neurodegenerative disease treatment, with improved water solubility and cytotoxic effects on tumoral cells. The berberine SD also demonstrated no cytotoxicity/genotoxicity in testing, suggesting it could be a safe option.

Leimann FV et al (2023).
Food Res Int.
PubMed:
37803607

Deep eutectic solvents as an alternative for extraction of flavonoids from soybean (Glycine max (L) Merrill) and okara: An experimental and computational approach based on COSMO-SAC model.

This study explores using Deep Eutectic Solvents (DES) for extracting flavonoids from soybean and okara. The DES [Ch]Cl: acetic acid with 30% water showed the highest flavonoid content and antioxidant activity. The COSMO-SAC model helped in solvent screening. DES can be a more eco-friendly alternative to traditional solvents.

Ferreira RSB et al (2023).
Food Res Int.
PubMed:
37803579

Natural food preservation with ginger essential oil: Biological properties and delivery systems.

This paper explores the potential of ginger essential oil as a natural food preservative, discussing extraction methods, chemical composition, antibacterial and antioxidant activities, and various applications in food preservation. Ginger essential oil offers effective preservation and improved release control ability, surpassing traditional methods.

He J et al (2023).
Food Res Int.
PubMed:
37803539

HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer.

Researchers identified the components in Dolomiaea costus extract and tested its effects on breast cancer cells and a virus. It has potential for cancer treatment and antiviral therapy.

El-Nashar HAS et al (2023).
BMC Complement Med Ther.
PubMed:
37803435

Characterization and expression profiles of WUSCHEL-related homeobox (WOX) gene family in cultivated alfalfa (Medicago sativa L.).

This study identified and analyzed 14 MsWOX transcription factors in alfalfa, showing their roles in various developmental processes and response to stress. The findings can guide further research in improving alfalfa growth and stress tolerance.

Xu A et al (2023).
BMC Plant Biol.
PubMed:
37803258

[Prediction and analysis of Q-markers of Elephantopus scaber based on its UPLC fingerprint, content determination of components, and in vitro a nti-tumor activity].

This study analyzed Elephantopus scaber using UPLC to determine its quality markers and identified 13 major components. The main components showed strong anti-cancer activity against lung cancer cells, making them potential quality markers for E. scaber.

Jia CC et al (2023).
Zhongguo Zhong Yao Za Zhi.
PubMed:
37802868

[Discovery, isolation and structural identification of alkaloid glycosides in six traditional Chinese medicine such as Coptis chinensis].

UPLC-QTOF-MS/MS identified 42 alkaloid glycosides, including two potentially new compounds, in traditional Chinese medicines. This aids in understanding their chemical composition and isolating alkaloid glycosides in other herbal medicines.

Wang R et al (2023).
Zhongguo Zhong Yao Za Zhi.
PubMed:
37802799

[New steroidal saponins from aerial parts of Paris polyphylla var. chinensis].

The researchers studied the chemical compositions of the aerial parts of Paris polyphylla var. chinensis and identified five new compounds. This research is important for the comprehensive utilization and development of waste parts of the plant.

Zheng ZL et al (2023).
Zhongguo Zhong Yao Za Zhi.
PubMed:
37802798