Hederasaponin C inhibits LPS-induced acute kidney injury in mice by targeting TLR4 and regulating the PIP2/NF-κB/NLRP3 signaling pathway.

Han S et al (2023).

Phytother Res.

DOI:

10.1002/ptr.8014

PubMed:

37778741

Toxicity and antitumor activity of the water-soluble lectin from Moringa oleifera Lam. Seeds (WSMoL) in sarcoma 180-bearing mice.

This study investigates the toxicity and antitumor activity of WSMoL, a lectin from Moringa oleifera seeds. Acute toxicity was seen at high doses, but no significant harm was observed at lower doses. WSMoL also reduced tumor weight and enhanced immune function in the tumor environment. This suggests that WSMoL may have potential as an antitumor agent.

Brito JS et al (2023).

Toxicon.

DOI:

10.1016/j.toxicon.2023.107306

PubMed:

37778740

The chromosome-level genome assembly of Fraxinus americana provides insights into the evolution of Oleaceae plants.

Zhang H et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.127132

PubMed:

37778585

Tomato growth and physiology as well as soil physicochemical and biological properties affected by ozonated water in a saline agroecosystem.

Díaz-López M et al (2024).

Sci Total Environ.

DOI:

10.1016/j.scitotenv.2023.167472

PubMed:

37778555

The raw and vinegar-processed Curcuma phaeocaulis Val. ameliorate TAA-induced zebrafish liver injury by inhibiting TLR4/MyD88/NF-κB signaling pathway.

Gao T et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117246

PubMed:

37778523

Effect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.

Crocus sativus (saffron) has been used as herbal medicine for T2DM in Sri Lanka. Systematic reviews and meta-analysis support its effectiveness, validating traditional knowledge.

Amatto PPG et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117255

PubMed:

37778521

Comparative effects of nutraceuticals on body weight in adults with overweight or obesity: A systematic review and network meta-analysis of 111 randomized clinical trials.

Various nutraceuticals, including spirulina, curcumin, psyllium, chitosan, and Nigella sativa, showed slight potential for weight improvement in overweight or obese adults. Green tea and glucomannan also resulted in small weight loss, but with less certainty. Nutraceutical supplementation could lead to modest weight loss in those with overweight or obesity.

Shahinfar H et al (2023).

Pharmacol Res.

DOI:

10.1016/j.phrs.2023.106944

PubMed:

37778464

Cactus flour (Opuntia ficus-indica) reduces brain lipid peroxidation and anxious-like behavior in old Wistar rats.

This study found that elderly rats fed with cactus flour showed reduced anxiety-like behavior and decreased brain lipid peroxidation. Cactus pear could potentially prevent or treat anxiety in aging individuals due to its nutritional contents.

Moura RL et al (2023).

Physiol Behav.

DOI:

10.1016/j.physbeh.2023.114360

PubMed:

37778453