Researchers developed a multifunctional composite using tadalafil-loaded nanoparticles (NPs) and ashwagandha extract in nanofibers. It improved wound closure, reduced inflammation, and enhanced angiogenesis in diabetic rats, offering potential as a diabetic wound dressing.
A study found 104 genes in the bHLH gene family in plants, classified into 23 subfamilies. Duplicated genes evolved under purifying selection and had similar structures. Some genes responded to cold stress and overexpression improved cold tolerance, providing insights into plant development and stress response.
The researchers analyzed the chloroplast genome of D. Don 1825, a medicinal plant used to treat various diseases. They found 131 genes and determined its phylogenetic relationship with other plants. This study provides a potential reference for important medicinal plants in the genus.
Engeletin from Smilax glabra shows antidepressant-like effects in mice by activating the BDNF-TrkB-mTORC1 pathway, enhancing synaptic plasticity in the prefrontal cortex. Promising as a new antidepressant.
Scientists studied the molecular basis of resistance to the emerald ash borer (EAB) in European ash trees. They found differential gene expression in susceptible and resistant genotypes, providing valuable information for managing the impending threat to this important tree species.