All Studies

Animal efficacy study of a plant extract complex (BEN815) as a potential treatment for COVID-19.

BEN815, a mixture of extracts from three plants, improved COVID-19 symptoms and increased survival rate in mice. It also reduced viral titers and showed potential as a safe treatment for SARS-CoV-2 in humans.

Do MH et al (2023).
PLoS One.
PubMed:
37708114

Next-generation sequencing reveals altered gene expression and enriched pathways in triple-negative breast cancer cells treated with oleuropein and oleocanthal.

Oleuropein and oleocanthal from extra-virgin olive oil inhibit the growth of triple-negative breast cancer cells. They alter gene expression and affect key pathways involved in cancer progression. Further research could explore their potential as alternative treatments for this aggressive form of breast cancer.

Karousi P et al (2023).
Funct Integr Genomics.
PubMed:
37707691

Evolutionary analysis of conserved non-coding elements subsequent to whole-genome duplication in opium poppy.

Researchers studied the evolutionary patterns of regulatory and coding sequences after whole-genome duplication in opium poppy. They found that regulatory element variations drove faster changes in gene expression patterns compared to coding sequences, with tissue-specific alkaloid production evolution being influenced by changes in regulatory elements. This study sheds light on the importance of regulatory element evolution in the development of new characteristics.

Xu Y et al (2023).
Plant J.
PubMed:
37706612

Single-cell RNA sequencing profiles reveal the developmental landscape of Manihot esculenta Crantz leaves.

Researchers created a detailed map of cassava leaf cells, identifying major tissue types and key genes involved in cell differentiation. This study helps understand cassava's photosynthetic and structural characteristics, essential for improving its yield and nutritional value.

Zang Y et al (2023).
Plant Physiol.
PubMed:
37706525

Cell cycle arrest and apoptotic studies of Terminalia chebula against MCF-7 breast cancer cell line: an in vitro and in silico approach.

Terminalia chebula fruit extract (TCF) shows potential as a targeted therapy for breast cancer, with antiproliferative effects and induction of apoptosis. Saccharopine, a phytochemical in TCF, has a higher binding affinity with EGFR. Promising for developing novel anticancer agents from plants.

Reddy P et al (2023).
Front Oncol.
PubMed:
37706181

Quality control, phytochemical profile, and biological activities of Crataegus monogyna Jacq. and Crataegus laciniata Ucria fruits aqueous extracts.

Both fruit extracts, rich in polyphenols, show antioxidant, antihyperglycemic effects, and antimicrobial activity against specific bacteria, suggesting their potential use in pharmaceuticals.

Zahrae Radi F et al (2023).
Saudi Pharm J.
PubMed:
37705878

Genome-wide identification and expression analysis of Hsp70 family genes in Cassava (Manihot esculenta Crantz).

In this study, researchers identified 22 Hsp70 genes in cassava and analyzed their functions. They found that these genes are involved in various cellular processes and play a role in stress tolerance and adaptation. This information can help scientists make informed decisions for their lab regarding stress management in cassava.

Muthusamy SK et al (2023).
3 Biotech.
PubMed:
37705861

Anti-Inflammatory Lindenane Sesquiterpenoid Dimers from the Roots of Sarcandra glabra.

Researchers discovered new compounds from the roots of a plant and determined their structures using various techniques. These compounds showed promising anti-inflammatory and anti-proliferation properties in the lab.

Sun Y et al (2023).
J Agric Food Chem.
PubMed:
37704568