Lindenane sesquiterpenoid dimers from Chloranthus holostegius with anti-neuroinflammatory activities in BV-2 microglia.
Scientists discovered fifteen previously unknown compounds, called chloranholides F-T, in the Chloranthus holostegius plant. These compounds show promising anti-inflammatory effects, inhibiting the production of the inflammatory mediator NO. Two specific compounds also suppressed the activity of iNOS and COX-2 enzymes.
- Zhan ZC et al (2023).
- Phytochemistry.
- PubMed:
- 37709158