Green synthesis of Piper nigrum copper-based nanoparticles: in silico study and ADMET analysis to assess their antioxidant, antibacterial, and cytotoxic effects.

This study used plants to create copper nanoparticles with antioxidant, antibacterial, and cytotoxic properties. The nanoparticles showed potential for scavenging free radicals, inhibiting bacteria, and being toxic to breast cancer cells. Certain components of the plant extract exhibited promising properties as inhibitors of selected proteins.

Kiranmayee M et al (2023).

Front Chem.

DOI:

10.3389/fchem.2023.1218588

PubMed:

37736256

The efferent connections of the orbitofrontal, posterior parietal, and insular cortex of the rat brain.

This study provides a digital resource of microscopic images from rat brain experiments, showing the structural connectivity of the orbitofrontal, posterior parietal, and insular cortices.

Reiten I et al (2023).

Sci Data.

DOI:

10.1038/s41597-023-02527-y

PubMed:

37735463

The oral administration of Lotus corniculatus L. attenuates acute and chronic pain models in male rats.

Researchers investigated the anti-inflammatory and analgesic effects of Lotus corniculatus L. extract. It may have potential as a natural remedy for peritoneal inflammation and back pain.

Jabbari S et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117181

PubMed:

37734474

Pathophysiology of diabetic hepatopathy and molecular mechanisms underlying the hepatoprotective effects of phytochemicals.

Herbal extracts like Moringa oleifera and Boswellia serrata have been shown to improve liver function in diabetes. They contain phenolic compounds that protect the liver through various mechanisms, including improving glucose metabolism and antioxidant defense.

Mobasheri L et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115502

PubMed:

37734266

Suppressive effect of Tripterygium hypoglaucum (Levl.) Hutch extract on rheumatoid arthritis in mice by modulating inflammasome and bile acid metabolism.

Zheng J et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115494

PubMed:

37734264

Graph Attention Network based mapping of knowledge relations between chemical spaces of Nuclear factor kappa B and Centella asiatica.

Researchers used deep learning and a graph-based system to study the immune system target NF-κB. They found nine molecules from Centella asiatica that could regulate NF-κB and need further investigation.

P V et al (2023).

Comput Biol Chem.

DOI:

10.1016/j.compbiolchem.2023.107955

PubMed:

37734134

Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer's disease.

Scientists developed tiny lipid carriers for a drug called donepezil hydrochloride, which could help treat Alzheimer's disease effectively. You should care because it could potentially improve the treatment of Alzheimer's disease.

Tekade AR et al (2023).

Drug Dev Ind Pharm.

DOI:

10.1080/03639045.2023.2262035

PubMed:

37733474

Transcriptome profiling reveals multiple regulatory pathways of Tamarix chinensis in response to salt stress.

Researchers studied the response of T. chinensis to salt stress and identified genes and pathways involved in salt tolerance. This study provides valuable insights for breeding salt-resistant plants.

Li R et al (2023).

Plant Cell Rep.

DOI:

10.1007/s00299-023-03067-w

PubMed:

37733273