All Studies

Molecular and Pharmacokinetic Aspects of the Acetylcholinesterase-Inhibitory Potential of the Oleanane-Type Triterpenes and Their Glycosides.

This study explores the acetylcholinesterase-inhibitory potential of various compounds found in the bark of (Combreatceae). Arjunetin and arjunglucoside I can cross the blood-brain barrier. These compounds show potential as cognition-enhancing agents and have a high binding energy. The kinetics of AChE inhibition were also tested.

Stępnik K, Kukula-Koch W and Płaziński W (2023).
Biomolecules.
PubMed:
37759757

Antimicrobial and antioxidant potential of the silver nanoparticles synthesized using aqueous extracts of coconut meat (Cocos nucifera L).

Researchers successfully synthesized silver nanoparticles using coconut meat extract. These nanoparticles exhibited significant antimicrobial properties against drug-resistant Candida and bacteria strains, making them potential candidates for therapeutic applications. Further investigation is required to determine their mode of action and biosafety.

Rizwana H et al (2023).
Sci Rep.
PubMed:
37758773

Study on network pharmacology of Ginkgo biloba extract against ischaemic stroke mechanism and establishment of UPLC-MS/MS methods for simultaneous determination of 19 main active components.

Ginkgo biloba extract (GBE) is effective for treating stroke, but we don't know the active ingredients or how it works. You should care because understanding its mechanism can help us develop better treatments.

Yin CY et al (2023).
Phytochem Anal.
PubMed:
37758241

Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study.

Licochalcone A (LCA), a compound from Glycyrrhiza uralensis, shows potential for treating esophageal cancer (EC). LCA inhibited EC cell proliferation, migration, and invasion while inducing apoptosis and cell cycle arrest. LCA also inhibited tumor growth in mice without major side effects. LCA can be a promising therapy for EC by regulating the p53 pathway.

Liu J et al (2023).
Eur J Pharmacol.
PubMed:
37758012