An efficient flavonoid glycosyltransferase NjUGT73B1 from Nardostachys jatamansi of alpine Himalayas discovered by structure-based protein clustering.
- Feng M et al (2024).
- Phytochemistry.
- PubMed:
- 39074762
Chinese medicine, when combined with other treatments, is effective in treating non-small cell lung cancer by reducing toxicity and increasing efficiency. Key components include Astragalus membranaceus, Wolfiporia cocos, and Atractylodes macrocephala, with potential therapeutic effects through AKT1 and EGFR targets.
Researchers identified 4 new compounds from Acronychia pedunculata leaves, 1 dimer and 3 monomers, along with 7 known analogues. Compound 5 showed strong anti-cancer effects with IC50 values from 0.24 to 5.3 μM against HCT-116, RKO, and SW480 cell lines.
Scientists developed a green microwave extraction method to recover bioactive compounds from hazelnut shells, which have nutraceutical properties. Optimal extraction conditions were identified to maximize phenolic content and antioxidant activity. This research is important for the production of high-quality natural extracts for nutraceutical formulations.