Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.

New compounds with anti-inflammatory properties were found in the roots of L. These compounds showed even better effectiveness than a commonly used anti-inflammatory drug. Additionally, five of these compounds helped to enhance the effects of certain chemotherapeutic drugs against cervical cancer cells, including those resistant to paclitaxel. The combination of one particular compound and paclitaxel successfully promoted cancer cell death through a specific cellular pathway. This research could lead to new treatments for inflammatory diseases and cancer, offering hope for improved patient outcomes.

Wan Q et al (2023).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.3c01667

PubMed:

37392181

Disruption of serotonin biosynthesis increases resistance to striped stem borer without changing innate defense response in rice.

Researchers found that a mutant rice resistant to the striped stem borer (SSB) lacks serotonin, which promotes SSB growth. This suggests that reducing serotonin levels could help breed SSB-resistant rice varieties.

Wang L et al (2023).

J Pineal Res.

DOI:

10.1111/jpi.12895

PubMed:

37392131

Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and In Silico insights.

Researchers studied the antiviral properties of Glycyrrhiza glabra, a herbal remedy, to develop new, safe, and effective drugs for various viral infections.

Elebeedy D et al (2023).

BMC Microbiol.

DOI:

10.1186/s12866-023-02911-z

PubMed:

37391715

Metabolomics Profiling of Tunisian Sonchus oleraceus L. Extracts and Their Antioxidant Activities.

Nouidha S et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202300290

PubMed:

37391386

1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface.

Yoon CH et al (2023).

Ocul Surf.

DOI:

10.1016/j.jtos.2023.06.016

PubMed:

37390940

Combined transcriptome and metabolome analysis reveal that the white and yellow mango pulp colors are associated with carotenoid and flavonoid accumulation, and phytohormone signaling.

Huang J et al (2023).

Genomics.

DOI:

10.1016/j.ygeno.2023.110675

PubMed:

37390936

Identification of Lipoxygenase gene repertoire of Cannabis sativa and functional characterization of CsLOX13 gene.

Fayaz M et al (2023).

Plant Sci.

DOI:

10.1016/j.plantsci.2023.111780

PubMed:

37390920

Therapeutic effects of Siegesbeckia orientalis L. and its active compound luteolin in rheumatoid arthritis: network pharmacology, molecular docking and experimental validation.

Xiao B et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.116852

PubMed:

37390879