Quality and Phytochemical Composition of Sweet Cherry Cultivars Can Be Influenced by Altitude.
- Nacouzi D, Masry R and El Kayal W (2023).
- Plants (Basel).
- PubMed:
- 37375880
The Carob tree, also known as "L'Kharrûb" in Morocco, has been traditionally used for treating various ailments. To understand its properties, we analyzed the chemical composition of the ethanolic extract of carob leaves (CSEE) and conducted several tests. The CSEE extract, rich in phenolic acids and flavonoids, exhibited potent antioxidant activity, comparable to ascorbic acid. It also showed broad-spectrum antibacterial activity but moderate effectiveness against fungi. Additionally, the extract demonstrated dose-dependent inhibition of human breast cancer cell lines. At lower concentrations, it did not induce DNA damage, but a higher concentration showed genotoxic effects. Computational analysis predicted potential biological activities and evaluated the toxicity of the extract's constituents. This research provides valuable insights into the medicinal properties of the Carob tree.
Roselle, a medicinal plant, has bioactive compounds with anti-hyperlipidemia, anti-hyperglycemia, and anti-hypertension effects. It may be a potential therapy for cardiovascular diseases.
A recent study investigated the potential of UD tea in combination with cisplatin as a treatment for breast cancer. The researchers conducted several tests on MDA-MB-231 breast cancer cells and found that the combination significantly reduced cell proliferation compared to each treatment alone. This effect was accompanied by increased signs of apoptosis, including changes in membrane composition and DNA fragmentation. Additionally, the study revealed that the combination increased DNA damage and altered the Bax/Bcl-2 ratio, further supporting the apoptotic mechanism. These findings suggest that UD tea could enhance the effectiveness of cisplatin in treating aggressive breast cancer.