Zn(II) Induces Fibril Formation and Antifungal Activity in Shepherin I, An Antimicrobial Peptide from Capsella bursa-pastoris.
Researchers found that the peptide shepherin I from shepherd's purse has strong antifungal activity when it binds with Zn(II) ions, causing a structural change and the formation of fibrils. This suggests a link between metal binding, morphology, and biological activity.
- Wątły J et al (2023).
- Inorg Chem.
- PubMed:
- 37983127