Antimicrobial Studies

Decoding the Multifaceted Potential of Artemisia monosperma: Comprehensive Insights into Allelopathy, Antimicrobial Activity, and Phytochemical Profile for Sustainable Agriculture.

Plant extracts inhibit weed growth, have antimicrobial properties, and could be used to manage weeds sustainably, promoting crop yield and environmental sustainability.

AntimicrobialPhytochemistry Amaranthus viridisChenopodium murale
El-Sheikh MA et al (2023).
Plants (Basel).
DOI:
10.3390/plants12213695
PubMed:
37960052

The antimicrobial effect and mechanism of the Artemisia argyi essential oil against bacteria and fungus.

Artemisia argyi essential oil was tested for antimicrobial activity. It demonstrated strong activity against various bacteria and Candida albicans. The oil disrupts the cytoderm and cytomembrane, making it effective as an antimicrobial agent.

AntimicrobialPhytochemistry Artemisia argyi
Li D et al (2023).
Braz J Microbiol.
DOI:
10.1007/s42770-023-01172-2
PubMed:
37957442

Synergistic Antimicrobial Activity of Eugenol in Combination with Fosfomycin to Combat Escherichia coli and Potential Effect on Plasmid-Mediated Fosfomycin Resistance Genes.

This study found that a combination of Eugenol (from Syzygium aromaticum) and Fosfomycin could effectively inhibit multidrug-resistant Uropathogenic Escherichia coli. The genes fosA3 and fosA4, which contribute to Fosfomycin resistance, were present in a small percentage of isolates. These findings suggest a potential new treatment for bacterial infections.

AntimicrobialGenetics Syzygium aromaticum
Ibrahim AA and Mohammed RK (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202301567
PubMed:
37956152

Antifungal efficacy of biogenic waste derived colloidal/nanobiochar against Colletotrichum gloeosporioides species complex.

This study investigated the inhibitory effects of corn cob and Gliricidia sepium wood colloidal/nanobiochar on Colletotrichum gloeosporioides. Results showed significant reductions in fungal growth, highlighting the potential for novel antifungal strategies in controlling anthracnose disease in bananas.

Antimicrobial Gliricidia sepium
Nishshankage K et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.117621
PubMed:
37952852

Discovery of the covalent SARS-CoV-2 M(pro) inhibitors from antiviral herbs via integrating target-based high-throughput screening and chemoproteomic approaches.

Lonicera japonica Flos extract contains gallic acid and quercetin, potent inhibitors of a coronavirus protein, offering a practical method to discover antiviral compounds from herbal medicines.

AntimicrobialCOVID-19 Lonicera japonica
Zhang YN et al (2023).
J Med Virol.
DOI:
10.1002/jmv.29208
PubMed:
37947293

Characterization of an antifungal β-1,3-glucanase from Ficus microcarpa latex and comparison of plant and bacterial β-1,3-glucanases for fungal cell wall β-glucan degradation.

Researchers discovered an antifungal enzyme (GlxGluA) in gazyumaru latex that degrades the cell wall of Trichoderma viride. Another enzyme (CcGluA) from Cellulosimicrobium cellulans degrades the cell wall of Saccharomyces cerevisiae. Understanding these enzymes could lead to improved strategies for controlling fungal infections in plants.

Antimicrobial Ficus microcarpa
Takashima T et al (2023).
Planta.
DOI:
10.1007/s00425-023-04271-4
PubMed:
37946063

Optimization and antifungal efficacy against brown rot fungi of combined Salvia rosmarinus and Cedrus atlantica essential oils encapsulated in Gum Arabic.

Nanoencapsulation of Salvia rosmarinus Speen and Cedrus atlantica Manetti essential oil mixture in Gum Arabic improves stability, antifungal activity against brown rot fungi, and thermal properties. Potential as a sustainable wood preservative for green building.

Antimicrobial Salvia rosmarinus
Annemer S et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-46858-7
PubMed:
37945688

Computational Approaches to Designing Antiviral Drugs against COVID-19: A Comprehensive Review.

This review explores the use of computational techniques and AI in developing antiviral agents for COVID-19. It identifies potential compounds and stresses the need for experimental validation to expedite the search for effective treatments.

AntimicrobialCOVID-19 Tinospora cordifolia
Singh MP et al (2023).
Curr Pharm Des.
DOI:
10.2174/0113816128259795231023193419
PubMed:
37916490
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