Asthma Studies

Canavalia gladiata Pod Extract Mitigates Ovalbumin-Induced Asthma Onset in Male BALB/c Mice via Suppression of MAPK.

Sword bean pod extracts (SBP) reduced inflammation in mice with allergic asthma, showing potential as a treatment option by suppressing key inflammatory proteins and cytokines.

Asthma Canavalia gladiata
Huang WY et al (2022).
Molecules.
DOI:
10.3390/molecules27196317
PubMed:
36234854

Rosa laevigata Attenuates Allergic Asthma Exacerbated by Water-Soluble PM by Downregulating the MAPK Pathway.

Water-soluble particulate matter (WPM) with heavy metals triggers severe inflammation and worsens asthma. Oral and intratracheal administration of RL reduces inflammation, secretion of cytokines, and IgE, suggesting potential as an asthma treatment.

Asthma Rosa laevigata
Ko HM et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.925502
PubMed:
35837279

Therapeutic potential of Ceratonia siliqua extract for the management of asthma and hypertension.

This study investigated the therapeutic effects of Carob pods on asthma and hypertension. The plant extract showed bronchorelaxant and vasorelaxant properties, and was safe to use without any adverse effects.

AsthmaCardiology Ceratonia siliqua
Hamid I et al (2022).
Cell Mol Biol (Noisy-le-grand).
DOI:
10.14715/cmb/2021.67.5.2
PubMed:
35818277

Anti-Inflammatory Food in Asthma Prepared from Combination of Raphanus sativus L., Allium hookeri, Acanthopanax sessiliflorum, and Dendropanax morbiferus Extracts via Bioassay-Guided Selection.

Researchers studied herbal plant extracts to create a nutraceutical that improves immune response to air pollutants, reducing inflammation in asthma. Their product successfully inhibited inflammatory cytokines in rat models, showing potential as a functional food for asthma treatment.

AsthmaImmunology Allium hookeri
Lee KD and Shim SY (2022).
Foods.
DOI:
10.3390/foods11131910
PubMed:
35804727

Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: Justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea.

Citrullus lanatus seeds have been traditionally used in Pakistan, India, and Sudan for treating digestive, respiratory, urinary issues, as well as bedwetting and urinary tract obstruction.

AsthmaEthnobotany Citrullus lanatus
Wahid M et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115314
PubMed:
35490899

Dual-Directional Regulation of Belamcanda chinensis Extract on Ovalbumin-Induced Asthma in Guinea Pigs of Different Sexes Based on Serum Metabolomics.

This study found that extract improved asthma symptoms in guinea pigs by affecting immune mechanisms, inflammation, nerve metabolism, and energy metabolism. The treatment effects varied based on sex.

Asthma Belamcanda chinensis
Liu J et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/5266350
PubMed:
35399628

Ethanolic Extract of Tridax procumbens Mitigates Pulmonary Inflammation via Inhibition of NF-κB/p65/ERK Mediated Signalling in an Allergic Asthma Model.

Tridax procumbens is a medicinal plant with anti-inflammatory properties. It effectively reduces oxidative stress and inflammation, but its impact on allergic asthma remains unclear.

AsthmaImmunology Tridax procumbens
Devi K et al (2022).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154008
PubMed:
35263673

Sesquiterpene lactones from Xanthium sibiricum Patrin alleviate asthma by modulating the Th1/Th2 balance in a murine model.

Scientists studied compound SL-XS from X. sibiricum, a traditional Chinese medicine, for its anti-asthma effects. Understanding its bioactive properties may lead to new treatments for asthma.

Asthma Xanthium sibiricum
Han J et al (2022).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154032
PubMed:
35263672
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