Asthma Studies

Heat shock cognate 70 protein like-2 protein in camphor pollen is one of the major culprits of asthma.

This study investigates the allergenic potential of camphor pollen, which is increasingly prevalent in Shanghai's street trees. Relevant if working with allergies or urban forestry.

Cao Y et al (2023).
Mol Immunol.
PubMed:
36933345

Shaoyao-Gancao-Tang regulates the T-helper-type 1/T-helper-type 2 ratio in the lung and gut and alters gut microbiota in rats with ovalbumin-induced asthma.

Shaoyao-Gancao Tang is a traditional Chinese medicine that effectively treats pain and asthma, but its exact mechanism of action remains unclear.

He R et al (2023).
J Ethnopharmacol.
PubMed:
36868437

Study on the Mechanism of Qing-Fei-Shen-Shi Decoction on Asthma Based on Integrated 16S rRNA Sequencing and Untargeted Metabolomics.

QFSS, a Chinese herbal formula, showed promising results in treating asthma in mice by regulating gut microbiota and metabolism. Potential mechanism for further research.

Hu H et al (2023).
Evid Based Complement Alternat Med.
PubMed:
36846048

Revealing the Underlying Mechanism of Acacia Nilotica against Asthma from a Systematic Perspective: A Network Pharmacology and Molecular Docking Study.

This study used network pharmacology and molecular docking to understand how AN (a folk cure for asthma) works. It identified key genes and pathways that AN interacts with to potentially treat asthma.

Alnusaire TS et al (2023).
Life (Basel).
PubMed:
36836768

Does pomegranate extract supplementation improve the clinical symptoms of patients with allergic asthma? A double-blind, randomized, placebo-controlled trial.

Pomegranate extract supplementation improved clinical symptoms and reduced immune cell counts in patients with allergic asthma, suggesting potential benefits for symptom management.

Hosseini SA et al (2023).
Front Pharmacol.
PubMed:
36762119

2-Undecanone alleviates asthma by inhibiting NF-κB pathway.

2-Undecanone can reduce airway inflammation and remodeling in asthma. It decreases inflammatory cells, cytokines, and inhibits NF-κB pathway, showing potential as a treatment.

Song G et al (2023).
Biochem Cell Biol.
PubMed:
36480816

A recombinant Artemisia vulgaris pollen adjuvanted Art v 1 protein-based vaccine treats allergic rhinitis and bronchial asthma using pre- and co-seasonal ultrashort immunotherapy regimens in sensitized mice.

The study evaluated a vaccine for allergic rhinitis and bronchial asthma, using an ultrashort treatment regimen. The vaccine showed significant reduction in symptoms and immune response polarization, suggesting potential efficacy. Further safety studies are recommended.

Babayeva M et al (2022).
Front Immunol.
PubMed:
36439113

Ephedra sinica polysaccharide alleviates airway inflammations of mouse asthma-like induced by PM2.5 and ovalbumin via the regulation of gut microbiota and short chain fatty acid.

This study examines the potential of Ephedra sinica polysaccharide (ESP) to mitigate lung damage caused by PM2.5 pollution, which is linked to asthma and other respiratory diseases.

Liu JX et al (2022).
J Pharm Pharmacol.
PubMed:
36301619
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