Traditional Chinese medicine combined with chemotherapy in the treatment of advanced non-small cell lung cancer: key drug screening and mechanism analysis.

Chinese medicine, when combined with other treatments, is effective in treating non-small cell lung cancer by reducing toxicity and increasing efficiency. Key components include Astragalus membranaceus, Wolfiporia cocos, and Atractylodes macrocephala, with potential therapeutic effects through AKT1 and EGFR targets.

Tang Y et al (2024).

Naunyn Schmiedebergs Arch Pharmacol.

DOI:

10.1007/s00210-024-03310-5

PubMed:

39073415

Prenylated Acetophenone Derivatives from the Leaves of Acronychia pedunculata and Their Anti-proliferative Activities.

Researchers identified 4 new compounds from Acronychia pedunculata leaves, 1 dimer and 3 monomers, along with 7 known analogues. Compound 5 showed strong anti-cancer effects with IC50 values from 0.24 to 5.3 μM against HCT-116, RKO, and SW480 cell lines.

Yang ZZ et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202401027

PubMed:

39073310

Network pharmacology- and molecular docking-based exploration of the molecular mechanism underlying Jianpi Yiwei Recipe treatment of gastric cancer.

TCM is important in cancer treatment. Network pharmacology helps study interactions of TCM components, useful for understanding multi-pathway and multi-target effects.

Chen P and Wu HY (2024).

World J Gastrointest Oncol.

DOI:

10.4251/wjgo.v16.i7.2988

PubMed:

39072163

Chemopreventive effect of modified zeng-sheng-ping on oral squamous cell carcinoma by regulating tumor associated macrophages through targeting tnf alpha induced protein 6.

Researchers developed a modified anti-cancer drug, ZSP-M, based on Zeng-Sheng-Ping, with high efficacy and low toxicity for oral cancer. They aim to understand its pharmacodynamic material basis and its effect on tumor-associated macrophages. This could lead to potentially effective treatments for oral squamous cell carcinoma.

Wang J et al (2024).

BMC Complement Med Ther.

DOI:

10.1186/s12906-024-04593-0

PubMed:

39068492

Investigating the anti-lung cancer properties of Zhuang medicine Cycas revoluta Thunb. leaves targeting ion channels and transporters through a comprehensive strategy.

Researchers studied Cycas revoluta Thunb. leaves for anti-cancer properties. Identified active constituents targeting ICTs in lung cancer. Important for developing new therapeutic options.

De L et al (2024).

Comput Biol Chem.

DOI:

10.1016/j.compbiolchem.2024.108156

PubMed:

39067352

Antimycobacterial and Anticancer Properties of Myrtus communis Leaf Extract.

Researchers studied the antimicrobial properties of plant-derived products, specifically focusing on a medicinal herb native to the Mediterranean region. Understanding these properties could lead to new treatments for infections and diseases.

Mir MA et al (2024).

Pharmaceuticals (Basel).

DOI:

10.3390/ph17070872

PubMed:

39065723

Anti-Inflammatory and Cancer-Preventive Potential of Chamomile (Matricaria chamomilla L.): A Comprehensive In Silico and In Vitro Study.

Study found chamomile tea may prevent cancer due to its anti-inflammatory properties. Worth investigating further for potential health benefits in cancer prevention.

Drif AI et al (2024).

Biomedicines.

DOI:

10.3390/biomedicines12071484

PubMed:

39062057

Bioprocessing of camptothecin from Alternaria brassicicola, an endophyte of Catharanthus roseus, with a strong antiproliferative activity and inhibition to Topoisomerases.

El-Hady NAAA et al (2024).

Microb Cell Fact.

DOI:

10.1186/s12934-024-02471-5

PubMed:

39060918