Cancer Studies

Green nanoarchitectonics of carbon quantum dots from Cinchona Pubescens Vahl as targeted and controlled drug cancer nanocarrier.

Researchers evaluated fluorescent carbon quantum dots (CQDs) as drug carriers for carboplatin delivery. CQDs can carry a high amount of carboplatin and have low cytotoxicity, making them promising for cancer treatment.

González-Reyna MA et al (2023).
Biomater Adv.
PubMed:
37515841

Extraction, Characterization, and Evaluation of the Cytotoxic Activity of Piperine in Its Isolated form and in Combination with Chemotherapeutics against Gastric Cancer.

Scientists have developed reliable, low-cost methods to extract piperine from black pepper. Piperine has shown good cytotoxic activity against aggressive gastric cancer cells, and can enhance the effectiveness of traditional chemotherapeutic drugs. It is a promising molecule for therapy investigations.

Ramos INF et al (2023).
Molecules.
PubMed:
37513459

The Antiproliferative Activity of Adiantum pedatum Extract and/or Piceatannol in Phenylhydrazine-Induced Colon Cancer in Male Albino Rats: The miR-145 Expression of the PI-3K/Akt/p53 and Oct4/Sox2/Nanog Pathways.

Adiantum pedatum extract and piceatannol protected against colon cancer by reducing oxidative damage, apoptosis, and histopathological changes in male albino rats. They may act through antioxidant and apoptotic pathways.

Khamis T et al (2023).
Molecules.
PubMed:
37513415

Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis.

Administration of the natural compound AR reduced the size and histological morphology of endometriosis lesions in an in vivo model. AR also reduced hyperproliferation, restored the impaired apoptosis pathway, and exhibited antioxidant, anti-inflammatory, and pain-reducing effects.

Interdonato L et al (2023).
Int J Mol Sci.
PubMed:
37511500

Exploring the Antimicrobial, Anticancer, and Apoptosis Inducing Ability of Biofabricated Silver Nanoparticles Using Lagerstroemia speciosa Flower Buds against the Human Osteosarcoma (MG-63) Cell Line via Flow Cytometry.

This study found that silver nanoparticles synthesized from flower buds have antimicrobial and anticancer properties, making them potential options for biomedical applications.

Shashiraj KN et al (2023).
Bioengineering (Basel).
PubMed:
37508848

Pepper Fruit Extracts Show Anti-Proliferative Activity against Tumor Cells Altering Their NADPH-Generating Dehydrogenase and Catalase Profiles.

Pepper fruits were found to have compounds that inhibit tumor cell growth, alter antioxidant capacity, and induce cell death.

Rodríguez-Ruiz M et al (2023).
Antioxidants (Basel).
PubMed:
37507999

Favorable Antitumor Activity of Citrus microcarpa B. on Human Colon Adenocarcinoma Tumor Xenografted in Immunosupressed Mice.

This study investigated the effect of Citrus microcarpa B. on human colon cancer tumors in immunosuppressed mice, finding potential antitumor activity.

Ples M, Santos M and Vitor Ii RJS (2023).
Asian Pac J Cancer Prev.
PubMed:
37505754