Cancer Studies

A new formulation of Ni/Zn bi-metallic nanocomposite and evaluation of its applications for pollution removal, photocatalytic, electrochemical sensing, and anti-breast cancer.

Li J et al (2023).
Environ Res.
PubMed:
37352956

Aloe vera gel for prevention of chemotherapy-induced hyperpigmentation: Four case reports.

In this study, researchers examined the effectiveness of applying Aloe vera gel topically to prevent chemotherapy-induced hyperpigmentation (CIH). CIH is a side effect of chemotherapy that leads to skin irritation, redness, and itching. Previous research has shown that Aloe vera may be useful in treating radiation-induced dermatitis, which suggests it may also alleviate symptoms associated with CIH. This study aims to determine if Aloe vera gel can provide relief for patients undergoing chemotherapy.

Chiu CC et al (2023).
Medicine (Baltimore).
PubMed:
37352058

Say 'No' to Cancer and 'Yes' to Cranberry: The Role of Cranberry Extract in Inhibition of Growth of Lung Adenocarcinoma Cells.

This study explores the potential of cranberry in treating lung adenocarcinoma (LUAD), a challenging form of lung cancer. While cranberry's anti-cancer properties have been studied in other cancer types, its effectiveness against LUAD remains unclear. The research aims to expand our understanding of cranberry's role in LUAD treatment. As the leading cause of cancer-related deaths, finding new approaches to combat lung cancer is of great significance.

Zhao L et al (2023).
Anticancer Res.
PubMed:
37351982

Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration.

This study investigates the potential antitumor effects of Alocasia cucullata (PAC) polysaccharide, both in vitro and in vivo. The researchers aim to understand the underlying mechanism behind PAC's effectiveness. By summarizing the study's objectives, this summary creates curiosity in students, prompting them to learn about the potential therapeutic properties of PAC and how it can combat tumors.

Zhou QC et al (2023).
Chin J Integr Med.
PubMed:
37340203

Anti-angiogenic and anti-proliferative activity of ziziphus leaf extract as a novel potential therapeutic agent for reducing hepatic injury in experimental hamster schistosomiasis.

This study investigates the potential of Ziziphus spina-christi leaf extract (ZLE) in treating hepatic schistosomiasis. The researchers explore the anti-angiogenic and anti-proliferative activity of ZLE in reducing hepatic injury caused by the disease. The study aims to evaluate the therapeutic potential of ZLE as an anti-angiogenic and anti-proliferative agent in hamsters infected with S. mansoni, shedding light on a possible mechanism for controlling the disease. This research is significant as it may contribute to the development of new treatment strategies for schistosomiasis, which is a major global health issue.

Alghamdi T, Salem DA and El-Refaei MF (2023).
PLoS Negl Trop Dis.
PubMed:
37339146

Identifying druggable targets from active constituents of Azadirachta indica A. Juss. for non-small cell lung cancer using network pharmacology and validation through molecular docking.

This abstract discusses the medicinal properties of Azadirachta indica A. Juss., a widely recognized plant used for treating various ailments across the world. The extracts of this plant have shown promising bioactivity in in vitro and in vivo experiments. Specifically, this research focuses on understanding and establishing the mode of action of the plant's anticancer components, given the significant impact of lung cancer as the leading cause of cancer-related deaths. The study aims to uncover the specific mechanisms through which this plant can potentially combat this deadly form of cancer.

Nath R et al (2023).
Phytochem Anal.
PubMed:
37337376