Cancer Studies

Mechanistic analyses reveal that Pueraria montana var. lobata (Willd.) is effective in inhibiting ovarian cancer progression.

The study explored the anti-tumor effects of P. montana var. lobata (Willd.) in ovarian cancer. Seven active ingredients were identified, along with key targets and pathways for potential treatment. Animal experiments showed promising results in inhibiting cancer progression. Further research and clinical trials are recommended.

CancerEndocrinology Pueraria montana
Lin C, Su T and Ye YJ (2024).
Naunyn Schmiedebergs Arch Pharmacol.
DOI:
10.1007/s00210-024-03158-9
PubMed:
38809293

In-silico evaluation of Oroxylum indicum vent compounds in the plausible treatment and prevention of nasopharyngeal cancer.

Researchers studied the plant Shyonaka for its anti-inflammatory, pain-relief, and anti-cancer properties. They found it could potentially target proteins related to both EBV replication and NPC proliferation, offering a promising treatment option for NPC patients.

Cancer Oroxylum indicum
Thrigulla SR et al (2024).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2024.100986
PubMed:
38805854

Glycyrrhiza Glabra Extract Modulates Type 1 T Helper (TH1) and Regulatory T Cell-Related Immune Responses in an Animal Model of Breast Cancer.

G. glabra can modulate immune cells to suppress TH1 and activate Treg cells, potentially inhibiting tumor development. Important for understanding and developing new cancer treatments.

Cancer Glycyrrhiza glabra
Yousefi S et al (2024).
Iran J Immunol.
DOI:
10.22034/iji.2024.101133.2735
PubMed:
38800958

Designing Green Synthesis-Based Silver Nanoparticles for Antimicrobial Theranostics and Cancer Invasion Prevention.

Researchers used plant-derived silver nanoparticles for antibacterial and anticancer effects. Biomolecules can be used to make nanoparticles biocompatible. Affordable and quick synthesis method with potential health benefits.

AntimicrobialCancer Neurada procumbens
Alomar TS et al (2024).
Int J Nanomedicine.
DOI:
10.2147/IJN.S440847
PubMed:
38799694

Angiogenic protein profiling, phytochemical screening and in silico anti-cancer targets validation of stem, leaves, fruit, and seeds of Calotropis procera in human liver and breast cancer cell lines.

Researchers studied C. procera for potential anticancer properties. Extracts showed antiangiogenic and anticancer capabilities with minimal side effects. Identifying novel targets for liver cancer treatment. Important for developing innovative medications.

CancerPhytochemistry Calotropis procera
Khan MF et al (2024).
Environ Res.
DOI:
10.1016/j.envres.2024.119180
PubMed:
38795948

Oxymatrine induces apoptosis in non-small cell lung cancer cells by downregulating TRIM46.

Oxymatrine from Sophora flavescens induces anti-tumor apoptosis in NSCLC cells by down-regulating TRIM46 and inhibiting the NF-κB pathway. This suggests potential for targeted cancer therapy.

Cancer Sophora flavescens
Zhong Y et al (2024).
Toxicon.
DOI:
10.1016/j.toxicon.2024.107773
PubMed:
38795848

Assessment of Anticancer Properties of Argemone mexicana L. and Berberine: A Comparative Study.

Berberine (BER) from L. showed cytotoxicity against tumor cells with low toxicity to normal cells. BER has anti-hemolytic and antioxidant effects. BER may be a promising chemotherapeutic agent.

Cancer Argemone mexicana
Elizondo-Luevano JH et al (2024).
Plants (Basel).
DOI:
10.3390/plants13101374
PubMed:
38794444

Comprehensive Chemical Profiling and Mechanistic Insight into Anticancer Activity of Annona muricata Leaves Extract.

Scientists analyzed the impact of leaf extract from L. on cancer in male mice. Extract contains unique compounds, improved expression of genes related to cell death, and protected against liver cancer. Exciting potential for anticancer agents.

Cancer Annona muricata
Abdallah RH et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17050614
PubMed:
38794184
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