Cancer Studies

Scutellarin, a flavonoid compound from Scutellaria barbata, suppresses growth of breast cancer stem cells in vitro and in tumor-bearing mice.

Scientists studied Scutellaria barbata to explore its potential as a natural treatment for various types of cancer. The compound scutellarin showed promise for its anti-tumor effects.

Ma H et al (2024).
Phytomedicine.
PubMed:
38518647

Prediction of potential mechanisms of rhubarb therapy for colorectal cancer based on network pharmacological analysis and molecular docking.

Study investigated potential targets and mechanism of Rheum palmatum L in treating colorectal cancer using network pharmacology and molecular docking. Identified key targets and components, suggesting potential therapeutic benefits through regulating multiple signaling pathways in colorectal cancer.

Yang F et al (2024).
Medicine (Baltimore).
PubMed:
38518016

Traditional Chinese medicine for gastric cancer: An evidence mapping.

Chinese Medicine has potential benefits for gastric cancer treatment, improving survival, myelosuppression, and immune function. More rigorous studies are needed, but integrating these interventions into clinical care may be beneficial.

Dai Z et al (2024).
Phytother Res.
PubMed:
38517014

Article review: Brazilin as potential anticancer agent.

Brazilin, a compound in traditional herbal medicine, shows promise as an anti-cancer agent with cytotoxic effects on various cancers and iron-chelating abilities. This research suggests brazilin could be a future chemo-preventive and anticancer treatment.

Raptania CN et al (2024).
Front Pharmacol.
PubMed:
38515856

Morinda citrifolia leaf assisted synthesis of ZnO decorated Ag bio-nanocomposites for in-vitro cytotoxicity, antimicrobial and anticancer applications.

MCL extract used to make ZnO nanoparticles and ZnO/Ag nanocomposites. ZnO/Ag NCs show strong antimicrobial activity against nosocomial bacteria and higher toxicity towards lung cancer cells compared to normal cells. Useful for developing antimicrobial and anticancer materials.

Venkatraman G et al (2024).
Bioprocess Biosyst Eng.
PubMed:
38509421

Ethanol extract of Eclipta prostrata induces multiple myeloma ferroptosis via Keap1/Nrf2/HO-1 axis.

Study showed Eclipta prostrata, a Chinese plant, has potential anti-tumor effects in multiple myeloma, a difficult-to-treat blood cancer. Could lead to new treatment options for MM patients.

Li W et al (2024).
Phytomedicine.
PubMed:
38507850

Portulaca oleracea L. polysaccharide inhibits ovarian cancer via inducing ACSL4-dependent ferroptosis.

L. polysaccharide inhibits ovarian cancer cell growth and migration by increasing lipid ROS and Fe levels, promoting ferroptosis via ACSL4. POL shows promise as a targeted ovarian cancer treatment.

Xia L, Yang M and Liu Y (2024).
Aging (Albany NY).
PubMed:
38503553

Withanone as an Emerging Anticancer Agent and Understanding Its Molecular Mechanisms: Experimental and Computational Evidence.

Researchers explored Withanone, a compound in Withania somnifera, as a potential safe cancer treatment. In silico and in vitro studies suggest anticancer activities and selective killing of cancer cells. Further research is needed for in vivo experiments and toxicity evaluation.

Stephen A et al (2024).
Curr Cancer Drug Targets.
PubMed:
38494932