Cancer Studies

Genetic activity and cytotoxic effect of Silybum marianum extract in comparison with the impact of antitumor drugs etoposide and methotrexate: a study on Drosophila melanogaster.

Researchers tested a plant extract's protective properties against cancer medications. Results show the extract reduces genotoxicity and enhances cytotoxic effects of the medications. This research could lead to improved treatment strategies.

Antosyuk ON, Sharova EA and Verbitskaya AK (2024).
Nat Prod Res.
PubMed:
38534126

Elucidating the anti-cancer potential of Cinnamomum tamala essential oil against non-small cell lung cancer: A multifaceted approach involving GC-MS profiling, network pharmacology, and molecular dynamics simulations.

Study identified active compounds in Indian Bay Leaf essential oil, targeting key genes in NSCLC. Shows potential as adjuvant therapy for lung cancer treatment, inducing apoptosis and inhibiting cell proliferation.

Mohanty D et al (2024).
Heliyon.
PubMed:
38533033

Exploring the combined anti-cancer effects of sodium butyrate and celastrol in glioblastoma cell lines: a novel therapeutic approach.

"SB and CEL inhibit DNA repair, induce apoptosis, and modulate autophagy in glioblastoma cells, showing potential as effective treatments. Important for developing new therapies for this aggressive brain cancer."

Kartal B et al (2024).
Med Oncol.
PubMed:
38532150

Exploring the potential of Ziziphus nummularia and luteolin-7-O-glucoside as tubulin inhibitors in cancer therapy and survival.

Ziziphus nummularia and Ziziphus spina-christi extracts show potential as anti-cancer agents, particularly ethanolic extract of Z. nummularia. Luteolin-7-O-glucoside is a promising candidate for further research due to its potent activity against cancer cells. Herbal treatment may activate cancer cell survival mechanisms.

Alghamdi SS et al (2024).
Sci Rep.
PubMed:
38531974

Scutellaria barbata D.Don extract regulates Ezrin-mediated triple negative breast cancer progress via suppressing the RhoA /ROCK1 signaling.

Researchers investigated the anti-cancer effects of Scutellaria barbata D.Don (SB) extract on triple-negative breast cancer (TNBC). Understanding its mechanism could lead to potential new treatment targets for TNBC.

Niu J, Hu J and Wang Z (2024).
Toxicol Res (Camb).
PubMed:
38525246

Evaluation of Efficacy of Curcumin and Caffeic Acid Phenethyl Ester in Breast Cancer by Preclinical Studies.

Researchers studied the effectiveness of CAPE and curcumin in treating breast cancer. Results could lead to new treatment options.

Verma SS et al (2024).
Curr Med Chem.
PubMed:
38523543

Effect of peppermint inhalation versus Swedish massage on chemotherapy induced-nausea and vomiting in children with leukemia: Multi-arm randomised trial design.

Chemotherapy effectively treats childhood leukemia but has major side effects like nausea and vomiting. Understanding and managing these side effects is critical for pediatric oncology care.

Badr EA et al (2024).
J Pediatr Nurs.
PubMed:
38518690