Research on different compound combinations of Realgar-Indigo naturalis formula to reverse acute promyelocytic leukemia arsenic resistance by regulating autophagy through mTOR pathway.

Li R et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117778

PubMed:

38310990

Hyperoside Inhibits RNF8-mediated Nuclear Translocation of β-catenin to Repress PD-L1 Expression and Prostate Cancer.

Hyperoside, found in Hypericum perforatum L., has potential anti-prostate cancer effects. This study examines its mechanisms in vitro and in vivo.

Chen J et al (2024).

Anticancer Agents Med Chem.

DOI:

10.2174/0118715206289246240110044931

PubMed:

38305391

SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/mTOR Signaling Pathways.

SSPH I, a saponin found in Schizocapsa plantaginea, has anti-proliferative and antimetastatic effects on lung cancer. This research suggests potential for developing new treatments.

Zhou J et al (2024).

Recent Pat Anticancer Drug Discov.

DOI:

10.2174/0115748928283132240103073039

PubMed:

38305308

Anti-tumor effect and mechanism of the total biflavonoid extract from S doederleinii on human cervical cancer cells in vitro and in vivo.

SDTBE, a biflavonoid extract from Hieron, inhibits cervical cancer cell proliferation, induces apoptosis, autophagy, and cell cycle arrest, and suppresses tumor growth in mice. The mechanism involves activating the Caspase-dependent mitochondrial apoptosis pathway.

Lin S et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e24778

PubMed:

38304845

Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.

Salvia miltiorrhiza Bunge, a Chinese herbal medicine, has known anti-tumor properties. However, the specific mechanism of how it inhibits tumor growth by preventing angiogenesis is still unclear.

Yu JR et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117791

PubMed:

38301987

A scoping review of Ayurvedic rasayana adaptogens in oncology.

This review examines current research on Ayurvedic rasayanas in oncology. It aims to summarize the literature, identify knowledge gaps, and highlight the adaptogenic effects of these natural products. Read it for insights on using rasayanas in your lab.

Wu C et al (2024).

J Ayurveda Integr Med.

DOI:

10.1016/j.jaim.2023.100879

PubMed:

38301299

Brucea javanica derived exosome-like nanovesicles deliver miRNAs for cancer therapy.

Exosome-like nanovesicles from B. javanica (BF-Exos) delivered microRNAs to cancer cells, slowing growth and metastasis. BF-Exos also inhibited angiogenesis. Promising for TNBC treatment.

Yan G et al (2024).

J Control Release.

DOI:

10.1016/j.jconrel.2024.01.060

PubMed:

38295998

Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.

Dehy, a compound from Saussurea lappa Clarke, effectively treats cancer and gastrointestinal disorders. However, its specific impact on gastric cancer is not well-known.

Chen Y et al (2024).

J Adv Res.

DOI:

10.1016/j.jare.2024.01.028

PubMed:

38295877