Artemisia annua L. Polyphenols Enhance the Anticancer Effect of β-Lapachone in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells.

Combining polyphenols extracted from Korean L. with β-lapachone enhances its anticancer effect on colorectal cancer cells, particularly those resistant to oxaliplatin. This combination inhibits proteins associated with resistance and promotes DNA damage, making it a potential low-toxicity therapy for oxaliplatin-resistant cancer.

Jung EJ et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms242417505

PubMed:

38139333

Effect of Petiveria alliacea Extracts on Metabolism of K562 Myeloid Leukemia Cells.

Scientists investigated the impact of on the metabolism of leukemic cells. They discovered that the extract reduced cell proliferation, altered metabolism, and decreased oxygen consumption and ATP levels, suggesting its potential as an anti-tumor agent. Care because it reveals the mechanisms behind its anti-tumor and antiproliferative effects.

Rojas L et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms242417418

PubMed:

38139247

Probing Antibacterial and Anticancer Potential of Selenicereus undatus, Pistacia vera L. and Olea europaea L. against Uropathogens, MCF-7 and A2780 Cancer Cells.

Study assesses antibiotic resistance and antibacterial effects of plant extracts on urinary tract infection-causing bacteria; extracts also exhibit potential for combating cancer cells. This research offers valuable insights for future treatments.

Safdar S et al (2023).

Molecules.

DOI:

10.3390/molecules28248148

PubMed:

38138636

Exploration of the effect and mechanism of Scutellaria barbata D. Don in the treatment of ovarian cancer based on network pharmacology and in vitro experimental verification.

Scutellaria barbata D. Don (SBD) contains bioactive ingredients that inhibit ovarian cancer development. Quercetin, luteolin, and wogonin are key components that inhibit cancer growth by targeting the PI3K/Akt signaling pathway. SBD could be a potential drug for ovarian cancer treatment.

Zhang J et al (2023).

Medicine (Baltimore).

DOI:

10.1097/MD.0000000000036656

PubMed:

38134066

Qilian Formula Inhibits Tumor Cell Growth in a Bone Metastasis Model of Lung Cancer.

Using the Qilian formula (AAF), Chinese folk medicine, researchers tested its inhibitory effect on tumor growth and osteoclast formation in advanced lung cancer with bone metastasis. Results may help protect bones and prevent pathological fractures.

Wang Q et al (2023).

Integr Cancer Ther.

DOI:

10.1177/15347354231217274

PubMed:

38130184

Preparation, characterization, and anticancer effects of an inclusion complex of coixol with β-cyclodextrin polymers.

Researchers investigated the potential of coixol, a compound found in a crop called L. var., as an anticancer agent. However, coixol's low solubility limits its use. This study aims to overcome this limitation for better therapeutic applications.

Wang XC et al (2024).

Pharm Biol.

DOI:

10.1080/13880209.2023.2294331

PubMed:

38126136

Preparation and investigation of a novel combination of Solanum nigrum-loaded, arabinoxylan-cross-linked β-cyclodextrin nanosponges for the treatment of cancer: in vitro, in vivo, and in silico evaluation.

Researchers developed a plant-based nanosponge that effectively treated breast cancer by inducing DNA damage, cell cycle arrest, and reducing tumor weight in mice, showcasing the potential of nanosponges as drug delivery systems in cancer treatment.

Shah HS et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1325498

PubMed:

38125886

Identification of EDNRA as the Key Biomarker for Hypercholesterolemia and Colorectal Cancer.

Han K et al (2024).

Tohoku J Exp Med.

DOI:

10.1620/tjem.2023.J101

PubMed:

38123303