Chemical Composition, In vitro and In silico evaluation of essential oil from Ocimum tenuiflorum and Coriandrum sativum Linn for lung cancer.

This paper analyzes the chemical composition and medicinal potential of essential oils from Ocimum tenuiflorum and Coriandrum sativum. Useful for understanding potential treatments for various diseases.

Singh B et al (2023).

Curr Comput Aided Drug Des.

DOI:

10.2174/1573409920666230831144716

PubMed:

37653637

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer.

Yi B et al (2023).

Front Immunol.

DOI:

10.3389/fimmu.2023.1238694

PubMed:

37649480

Assessing the potential of rosary pea (Abrus precatorius L.) derived aqueous seed extracts as anticancer agents and their phytoconstituents as COX-2 inhibitor: an in-vitro and in-silico approach.

L. is a medicinal remedy with diverse bioactivities. Aqueous seed extracts have high antioxidant, antiproliferative, antiangiogenic properties. They show potential as anticancer and antiangiogenic drugs.

Kaur A et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2251053

PubMed:

37649393

RNA Sequencing and Bioinformatics Analysis Reveals the Downregulation of DNA Replication Genes by Morindone in Colorectal Cancer Cells.

Morindone, a natural compound, shows promise as a treatment for colorectal cancer (CRC). It downregulates genes involved in DNA replication and cell development. GINS2 is identified as a potential target. Validation confirms these findings. Consider using morindone for CRC treatment.

Chee CW et al (2023).

Appl Biochem Biotechnol.

DOI:

10.1007/s12010-023-04690-9

PubMed:

37642925

Antitumor and antibacterial activity of metabolites of endophytic Colletotrichum siamense isolated from coffee (Coffea arabica L. cv IAPAR-59).

Researchers analyzed the chemical profile of endophytic fungus Colletotrichum siamense from coffee plants and found potential compounds with pharmacological and antibacterial activity. This could be beneficial for the pharmaceutical and biotechnological industries.

do Espírito Santo BC et al (2023).

Braz J Microbiol.

DOI:

10.1007/s42770-023-01104-0

PubMed:

37642890

Tribulus terrestris L. induces cell apoptosis of breast cancer by regulating sphingolipid metabolism signaling pathways.

Study investigated the effects of Tribulus terrestris extract on breast cancer. Provides evidence for the traditional use of TT as a potential treatment, highlighting its pharmacological activities in breast cancer.

Zhao J et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155014

PubMed:

37639811

Integrating Network Pharmacology and Experimental Validation to Explore the Effects and Mechanisms of Qinghao Biejia Decoction and Its Active Compound Artemisinin B Against Non-Small-Cell Lung Cancer.

Researchers used network pharmacology to investigate the effects of Qinghao Biejia decoction (QBD) against lung cancer and examined the anticancer impact of artemisinin B on H1299 cells. The study sheds light on the potential use of QBD and artemisinin B in treating non-small-cell lung cancer.

Ye Y et al (2023).

Drug Des Devel Ther.

DOI:

10.2147/DDDT.S414098

PubMed:

37637262

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer.

Scientists studied urothelial carcinoma (UC) in dogs, cats, and cattle exposed to a carcinogen. UC in these animals share similarities with aggressive bladder cancer in humans. Understanding these models can help develop strategies to identify key factors driving the disease in humans.

Wong K et al (2023).

Genome Biol.

DOI:

10.1186/s13059-023-03026-4

PubMed:

37635261