Cardiology Studies

Atractylenolide-I Alleviates Hyperglycemia-Induced Heart Developmental Malformations through Direct and Indirect Modulation of the STAT3 Pathway.

Atractylenolide-I from Baizhu herb may prevent congenital heart defects in infants of mothers with gestational diabetes. Potential for new preventive and therapeutic treatments.

Wang M et al (2024).
Phytomedicine.
PubMed:
38728919

Simultaneous Exposure to Noise and Toluene Induces Oxidative and Inflammatory Damage in the Heart of Wistar Rats: Therapeutic Potential of Olea europaea L. Leaf Extract.

TL;DR: Study showed combined exposure to noise and toluene harms heart health in rats, but treatment with OLE leaf extract reduced oxidative damage and inflammation. OLE may protect against occupational risks for workers.

Ben Attia T et al (2024).
Cardiovasc Toxicol.
PubMed:
38722494

Panax quinquefolius saponins and panax notoginseng saponins attenuate myocardial hypoxia-reoxygenation injury by reducing excessive mitophagy.

Researchers studied the effects of PQS and PNS from ginseng on heart injury. Results suggest potential protection against heart damage from lack of oxygen, making them promising treatments for ischemic heart conditions.

Xia J et al (2024).
Cell Biochem Biophys.
PubMed:
38713401

A Systematic Review of Herbal Interventions for the Management of Cardiovascular Diseases.

Researchers reviewed herbal interventions for managing cardiovascular diseases (CVDs), highlighting their safety, therapeutic potential, and clinical relevance as adjuncts or alternatives to conventional treatments.

Wal A et al (2024).
Curr Cardiol Rev.
PubMed:
38706368

Ecdysterone improves oxidative damage induced by acute ischemic stroke via inhibiting ferroptosis in neurons through ACSL4.

Researchers studied the effects of Ecdysterone from Achyranthes bidentata Blume on acute ischemic stroke (AIS). EDS shows antioxidant and anti-cerebral hypoxia properties, potentially improving AIS outcomes. This research may lead to new therapies for stroke patients.

Sun J et al (2024).
J Ethnopharmacol.
PubMed:
38679397

Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.

Researchers studied the effects of processed Danshen (DS) with porcine cardiac blood (PCB-DS) on Cerebral ischemia-reperfusion injury (CIRI) in strokes. PCB-DS showed potential anti-ischemic effects, but the mechanism is still unknown.

Zhou S et al (2024).
Phytomedicine.
PubMed:
38677272

The Therapeutic Potential of Four Main Compounds of Zanthoxylum nitidum (Roxb.) DC: A Comprehensive Study on Biological Processes, Anti-Inflammatory Effects, and Myocardial Toxicity.

Research on compounds from shows potential therapeutic effects in cardiovascular diseases, including anti-inflammatory properties and impact on ion channels in cardiomyocytes. Findings suggest using these compounds for cardiovascular treatment.

Li X et al (2024).
Pharmaceuticals (Basel).
PubMed:
38675484

Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress.

Silymarin protects against paracetamol-induced liver and heart damage by reducing oxidative stress markers and restoring antioxidant enzyme activity. Potentially valuable therapeutic agent for liver and heart diseases.

Okiljević B et al (2024).
Pharmaceutics.
PubMed:
38675181