Covid-19 Studies

A multicenter analysis on the changes of sIgE in China during the early period of COVID-19 pandemic.

Study analyzed changes in allergen composition ratio during early stages of COVID-19 outbreak in China. Identified factors contributing to these alterations. Useful for understanding the impact of the pandemic on allergens and related allergies.

Li Y and Li L (2023).
Immun Inflamm Dis.
PubMed:
38018584

Individualized homeopathic medicines in the treatment of post-COVID-19 fatigue in adults: A single-blind, randomized, placebo-controlled trial.

This trial investigates the effectiveness of homeopathic medicines compared to placebos for treating post-COVID-19 fatigue in adults. Results could provide insights on managing this challenging condition.

Saha S et al (2023).
Complement Med Res.
PubMed:
38008074

The influence of propolis plus Hyoscyamus niger L. against COVID-19: A phase II, multicenter, placebo-controlled, randomized trial.

Propolis syrup with Hyoscyamus niger L. extract reduced COVID-19 symptoms, improved oxygen levels, and shortened hospital stays in 140 patients, suggesting it as a potential treatment.

Kosari M et al (2023).
Phytother Res.
PubMed:
37992760

Chemical Composition of Rosemary (Rosmarinus officinalis L.) Extract and Its Inhibitory Effects on SARS-CoV-2 Spike Protein-ACE2 Interaction and ACE2 Activity and Free Radical Scavenging Capacities.

Rosemary water extract contains compounds that inhibit the interaction between the SARS-CoV-2 spike protein and ACE2, as well as reduce ACE2 activity. This suggests that rosemary may lower the risk of COVID-19 infection and development.

Yao Y et al (2023).
J Agric Food Chem.
PubMed:
37988686

Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication.

Compounds from the hop plant, including xanthohumol, have strong antiviral effects. XN specifically shows promise in inhibiting the main protease of SARS-CoV-2. This could be valuable for developing potential treatments against COVID-19.

Herzog AM et al (2023).
Phytomedicine.
PubMed:
37976697

Nigella sativa and its chemical constituents: pre-clinical and clinical evidence for their potential anti-SARS-CoV-2 effects.

Nigella sativa (NS) extracts contain compounds that can potentially prevent SARS-CoV-2 from entering host cells, treat COVID-19 symptoms, and target key proteins. This review summarizes pre-clinical and clinical studies on NS and its potential therapeutic role against COVID-19.

Cyril AC et al (2023).
Inflammopharmacology.
PubMed:
37966624

A review: Mechanism and prospect of gastrodin in prevention and treatment of T2DM and COVID-19.

Gastrodin, a Chinese herb extract, has anti-inflammatory, antioxidant, and antiviral properties, outperforming diabetes medications with fewer side effects. It protects lung function, improves antiviral activity, and inhibits a factor in COVID-19 complications. Promising as a diabetes and COVID-19 treatment.

Li Y, Ji Y and Li F (2023).
Heliyon.
PubMed:
37954278

Discovery of the covalent SARS-CoV-2 M(pro) inhibitors from antiviral herbs via integrating target-based high-throughput screening and chemoproteomic approaches.

Lonicera japonica Flos extract contains gallic acid and quercetin, potent inhibitors of a coronavirus protein, offering a practical method to discover antiviral compounds from herbal medicines.

Zhang YN et al (2023).
J Med Virol.
PubMed:
37947293