Diabetes Studies

Evaluation of phytochemical profile, and antioxidant, antidiabetic activities of indigenous Thai fruits.

Thai fruits were analyzed for phenolics and flavonoids to explore their potential in treating type 2 diabetes. These lesser-known fruits could offer health benefits and be useful in diabetes management.

DiabetesImmunologyPhytochemistry Dillenia indicaMuntingia calaburaPhyllanthus reticulatusSyzygium cuminiSyzygium malaccense
Prakulanon J et al (2024).
PeerJ.
DOI:
10.7717/peerj.17681
PubMed:
39011385

Aldose reductase inhibitory and antiglycation properties of phytoconstituents of Cichorium intybus: Potential therapeutic role in diabetic retinopathy.

Study on C. intybus extract for diabetic retinopathy: inhibits AR enzyme, reduces advanced glycation end products, and shows strong therapeutic potential. Potential for drug development against diabetic vascular complications.

Diabetes Cichorium intybus
Ahmad S et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.133816
PubMed:
39002911

Supplementation with Highly Standardized Cranberry Extract Phytosome Achieved the Modulation of Urinary Tract Infection Episodes in Diabetic Postmenopausal Women Taking SGLT-2 Inhibitors: A RCT Study.

"Cranberry extract may reduce UTI recurrence in diabetic postmenopausal women taking SGLT-2 inhibitors. No impact on glycemic control or quality of life. Consider supplement for prevention."

DiabetesEndocrinology Vaccinium macrocarpon
Rondanelli M et al (2024).
Nutrients.
DOI:
10.3390/nu16132113
PubMed:
38999860

Lingonberry (Vaccinium vitis-idaea L.) Skin Extract Prevents Weight Gain and Hyperglycemia in High-Fat Diet-Induced Model of Obesity in Mice.

Lingonberry extract from juice by-product can help prevent weight gain and improve glucose tolerance in high-fat diet-induced obese mice. Potential for combating obesity-related health issues, further research required for health applications.

DiabetesObesity Vaccinium vitis-idaea
Ryyti R et al (2024).
Nutrients.
DOI:
10.3390/nu16132107
PubMed:
38999854

Structural characterization and hypoglycemic effect of polysaccharides of Polygonatum sibiricum.

Researchers extracted and analyzed Polygonatum sibiricum polysaccharide (PSP) for its potential benefits in diabetes treatment. PSP inhibits enzymes, improves insulin sensitivity, and repairs tissue damage in diabetic mice. PSP shows promise as a natural therapeutic agent for type II diabetes.

Diabetes Polygonatum sibiricum
Wang X et al (2024).
J Food Sci.
DOI:
10.1111/1750-3841.17243
PubMed:
38992877

Profiling of Antidiabetic Bioactive Flavonoid Compounds from an Edible Plant Kudzu (Pueraria lobata).

Researchers isolated flavonoids from kudzu plant and found they lower blood sugar levels and may treat diabetes by targeting SGLT2, PTP1B, and AG enzymes. This study provides insight into the plant's potential health benefits.

DiabetesPhytochemistry Pueraria lobata
Wang W et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c02564
PubMed:
38976778

Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.

Chinese herb kidney tea may offer new treatment options for diabetic nephropathy, a leading cause of end-stage renal disease. Further research needed to understand its mechanisms and potential as a therapeutic agent.

DiabetesGastroenterology Orthosiphon aristatus
Zhou Z et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1392123
PubMed:
38962302

Mango peel extracts and mangiferin chromatographic Fourier-transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico modeling and in vitro assays.

Mango peel waste contains potent antidiabetic compounds, with Langra variety exhibiting strong α-glucosidase inhibition and Langra and Sindhri varieties showing advanced glycation end product inhibition. These findings suggest potential for diabetes management.

DiabetesImmunology Mangifera indica
Amin A et al (2024).
Biomed Chromatogr.
DOI:
10.1002/bmc.5936
PubMed:
38956791
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