Diabetes Studies

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.

Researchers studied the effects of CQR-300 from vining plant on T2DM in mutated mice. CQR-300 reduced blood glucose, insulin levels, inhibited gluconeogenesis, lipogenesis, and oxidative stress. Potential as T2DM supplement.

Kim JW et al (2024).
Front Pharmacol.
PubMed:
39050759

Antidiabetic Activity, Phytochemical Analysis, and Acute Oral Toxicity Test of Combined Ethanolic Extract of Syzygium polyanthum and Muntingia calabura Leaves.

Combined ethanolic extract of and leaves showed strong antidiabetic activity by inhibiting -glucosidase enzyme and lowering blood glucose levels in rats, indicating potential for herbal medication development. Phytochemical analysis confirmed high levels of total phenolics, flavonoids, and quercetine.

Widodo A et al (2024).
ScientificWorldJournal.
PubMed:
39050386

Elemental Profiling of Common Anti-diabetic Medicinal Plants of Swat and Peshawar Districts of Khyber Pakhtunkhwa (KPK) Province of Pakistan: An Investigation Using PIXE and ICP-OES.

Study analyzed elemental composition of 16 anti-diabetic plants using PIXE and ICP-OES. Plants contain essential elements such as Zn and Se crucial for glucose metabolism and insulin function. Results support their use in diabetes management.

Zubair A et al (2024).
Biol Trace Elem Res.
PubMed:
39037503

Atractylodes macrocephala Koidz. and Cuscuta chinensis Lam. extract relieves insulin resistance via PI3K/Akt signalling in diabetic Drosophila.

Researchers studied the effect of AMK-CCL extract on insulin resistance in a diabetic fly model. Results suggest potential for treating T2DM. Further research warranted.

Li Y et al (2024).
J Tradit Complement Med.
PubMed:
39035690

Therapeutic effects of OXY- Exo(Aloe) in diabetic wound injury.

OXY-Exo, made from aloe vera gel, ginger juice, and neem fruit sap, accelerates diabetic wound healing by increasing oxygenation, reducing inflammation, and promoting tissue remodeling. Safe and effective, it has no reported side effects.

Miya MB et al (2024).
Biochem Biophys Res Commun.
PubMed:
39032360

Eco-friendly Nanoparticles Synthesized from Salvia sclarea Ethanol Extract Protect against STZ-induced Diabetic Nephropathy in Rats via Antioxidant, Anti-inflammatory, and Apoptosis Mechanisms.

Researchers developed eco-friendly silver nanoparticles using Salvia sclarea extract, showing protective effects against diabetic nephropathy in rats. The nanoparticles reduced blood glucose, inflammation, oxidative stress, and apoptosis in renal cells. This study highlights the potential of EESS AgNPs for treating diabetes complications.

Ma Y et al (2024).
J Oleo Sci.
PubMed:
39019617

A novel chitosan-PEG hydrogel embedded with in situ silver nanoparticles of Clerodendrum glandulosum Lindl. extract: evaluation of its in vivo diabetic wound healing properties using an image-guided machine learning model.

Researchers developed a new hydrogel for diabetic wound healing. It showed controlled release, antioxidant, antimicrobial, and wound healing properties, promising faster wound closure and improved extracellular matrix formation. Ideal for novel topical formulation.

Majie A et al (2024).
Biomater Sci.
PubMed:
39011583