Diabetes Studies

Polysaccharide extracted from Sarcandra glabra residue attenuate cognitive impairment by regulating gut microbiota in diabetic mice.

SERP from Sarcandra glabra improves cognitive function in diabetic encephalopathy by regulating gut microbiota, lipid metabolism, and butyric acid levels. Promising treatment option targeting "microbiota-gut-brain axis".

Ye M et al (2024).
Int J Biol Macromol.
PubMed:
38719002

Paris polyphylla Sm. characterized extract infused ointment accelerates diabetic wound healing in In-vivo model.

Scientists studied the potential anti-inflammatory and anticancer properties of Paris polyphylla Sm. rhizome, supporting traditional medicinal uses. This research could lead to the development of new treatments for various conditions.

Kshetrimayum V et al (2024).
J Ethnopharmacol.
PubMed:
38710458

Bletilla striata Polysaccharide-/Chitosan-Based Self-Healing Hydrogel with Enhanced Photothermal Effect for Rapid Healing of Diabetic Infected Wounds via the Regulation of Microenvironment.

Researchers developed a innovative wound dressing using a self-healing hydrogel with nanoparticles to fight infection and promote healing in diabetic ulcers. It shows promising results in studies and may have clinical benefits.

Zhao K et al (2024).
Biomacromolecules.
PubMed:
38700942

Antidiabetic and hepatoprotection effect of butterfly pea flower (Clitoria ternatea L.) through antioxidant, anti-inflammatory, lower LDH, ACP, AST, and ALT on diabetes mellitus and dyslipidemia rat.

Butterfly pea flower extract (CTE) shows potential for treating diabetes and protecting the liver in rat models. It has anti-inflammatory, antioxidant, and anti-diabetic properties. CTE improved liver function and reduced oxidative stress markers in rats with diabetes and dyslipidemia.

Widowati W et al (2024).
Heliyon.
PubMed:
38681657

Plantaginis Semen ameliorates diabetic kidney disease via targeting the sphingosine kinase 1/sphingosine-1-phosphate pathway.

Researchers studied the medicinal properties of Plantaginis Semen (PS) in China for diuretic, anti-hypertensive, anti-hyperlipidemic, and anti-hyperglycemic effects. Limited research on its therapeutic mechanisms warrants further investigation.

Lan JP et al (2024).
J Ethnopharmacol.
PubMed:
38677576

Restoring bone-fat equilibrium: Baicalin's impact on P38 MAPK pathway for treating diabetic osteoporosis.

Baicalin from Scutellaria baicalensis helps treat diabetic osteoporosis by promoting bone formation and inhibiting fat accumulation. Its effects may be mediated through the P38-MAPK pathway, offering a potential new treatment approach.

Qin W et al (2024).
Biomed Pharmacother.
PubMed:
38677248

Structure-based virtual screening of mangiferin derivatives with antidiabetic action: a molecular docking and dynamics study and MPO-based drug-likeness approach.

HMF and other mangiferin derivatives exhibit strong antidiabetic properties by inhibiting aldose reductase with promising drug-like properties and low toxicity. HMF stands out for its high affinity and stability, making it a promising candidate for diabetes treatment.

da Silva Lopes FF et al (2024).
3 Biotech.
PubMed:
38665880

Metabolite profiling, antioxidant and anti-glycemic activities of Tartary buckwheat processed by solid-state fermentation(SSF)with Ganoderma lucidum.

Fermentation of Tartary buckwheat increased enzyme activity, bioactive compounds, and metabolite diversity. Results show improved antioxidant and anti-glycemic properties. Fermentation could enhance health benefits of Tartary buckwheat.

Zhang R et al (2024).
Food Chem X.
PubMed:
38665636