Researchers collected data on 50 derivatives of kaempferol, a flavonoid found in plants, and performed a 3D-QSAR study. They found that certain derivatives showed potential as anti-diabetic and antibacterial agents. The compounds could be used for drug discovery.
Researchers conducted virtual screenings and molecular dynamics investigations to discover natural inhibitors of α-amylase and α-glucosidases for diabetes management. Rutin from the MC plant exhibited the highest binding affinity and could potentially be an effective therapeutic agent for diabetes. Further research is needed to validate its efficacy.
SnO nanoparticles using Artemisia vulgaris as a stabilizing agent inhibit biofilm formation in drug-resistant Candida albicans strains, potentially treating biofilm-related diabetic foot ulcers. They aid in wound healing.
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The study found that the ethanolic Terminalia chebula extract reduced oxidative stress, improved brain integrity, and decreased abnormal changes in the brains of diabetic rats. This suggests that T. chebula extract could potentially be beneficial for the treatment of diabetes-related neuroinflammation.
HKC, a Chinese medicine made from abelmoschus extracts, shows potential in treating diabetic nephropathy. Flavonoids in HKC were identified and their metabolism studied in diabetic mice, providing insights for improving DN treatment.
Researchers investigated the effects of Tribulus terrestris L. (TT) fruit on diabetes. TT has been used in Tibetan medicine for centuries, but its mechanisms and effects on diabetes remained unknown.
Bitter orange leaves were extracted using different methods to compare their chemical composition. The essential oils showed antioxidant and antidiabetic activities, making them potential sources for future drugs.